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BIOGESIC Paracetamol 100mg / mL Suspension (Oral Drops) 15mL Orange

NONRXDRUG-DRHR-1167
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Description

Indications/Uses

See Table 1.
 

 

Dosage/Direction for Use

These medicines should be taken orally every 4 hours, as needed for pain and/or fever, or, as directed by a doctor.
Dosing in Children: 10 mg/kg body weight per dose given every 4 hours, as needed, not to exceed 5 doses in each 24-hour period; or, follow the dose in the dosing table as follows: See Table 2.



Missed Dose: If there is a missed dose, take the next dose if still needed for pain and/or fever and the subsequent doses every 4 to 6 hours thereafter.
Do not double the dose.
 

Overdosage

Overdosage of paracetamol usually involves four phases with the following signs and symptoms: Reduced or loss of appetite, nausea, vomiting, malaise (a general feeling of being unwell), and excessive sweating; Right upper abdominal pain or tenderness, liver enlargement which may be characterized by abdominal discomfort of "feeling full", elevated bilirubin and liver enzyme concentrations, prolongation of prothrombin time, and occasionally decreased urine output; Reduced or loss of appetite, nausea, vomiting, and malaise recur (usually three to five days after initial symptom onset); signs of liver failure (e.g., jaundice, hypoglycemia, coagulopathy, encephalopathy), and possibly kidney failure and cardiomyopathy (disorder of the heart muscle) may develop; Recovery or progression to fatal complete liver failure.
Metabolic acidosis (excessive acid in the body), encephalopathy (abnormal brain function), increased methemoglobin (kind of red blood cells) in the blood, and coma may also occur. Clinical and laboratory signs of liver toxicity may not be apparent 48 to 72 hours after ingestion.
If the patient has taken more than the recommended dosage, consult a doctor or contact a poison control center right away, even if the patient seems well, as there is a risk of delayed serious liver damage. Quick medical attention is important for adults as well as for children even if the patient do not notice any signs or symptoms.
 

Administration

May be taken with or without food.
 

Contraindications

If the patient is allergic to paracetamol or any ingredient in the product.
If the patient is taking other medicines that contain paracetamol.
If the patient has anemia or with heart, lung, kidney, or liver disease, unless recommended by a doctor.
 

Special Precautions

Liver Warning: This product contains paracetamol. Severe liver damage may occur if: A child takes more than 5 doses in 24 hours, which is the maximum daily amount; An adult or child 12 years old and above takes more than 4 g of paracetamol in 24 hours; Taken with other medicines containing paracetamol (or acetaminophen).
Allergy alert: Paracetamol may cause severe skin reactions. Symptoms may include: Skin reddening; Blisters; Skin rash or hives; Swelling of the face, tongue or throat; Difficulty swallowing; Unexplained wheezing or shortness of breath.
Ask a doctor before use if patient has liver or kidney disease.
Use with caution in patients with glucose-6-phosphate deficiency (G6PD).
Do not take more than the recommended dose.
Ask a doctor before use if: The patient has kidney or liver problems.
The patient suffers from mild arthritis and need to take pain relievers every day.
The patient is taking any other medicines (See Interactions).
The patient has glucose-6-phosphate deficiency (G6PD).
The cause of the patient's illness is not clear or it is accompanied by a rash, breathing difficulties, diarrhea or excessive tiredness or lethargy.
The patient is severely malnourished, anorexic, and has a low body mass index, or excessively drinks alcohol.
Stop use and ask a doctor if: If symptoms of allergic reaction occur, stop use and seek medical help right away.
Symptoms worsen or do not improve.
New symptoms occur.
Any undesirable effect occurs.
Redness or swelling is present.
Fever gets worse or lasts more than 3 days.
Pain gets worse or lasts more than 5 days in children.
Patient had unexpected bruising or bleeding, and had more infections than usual.
Consult a doctor promptly if sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting.
 

Adverse Reactions

Paracetamol, when taken within the recommended dose and duration of treatment, has low incidence of side effects. The most common side effects are constipation, headache, insomnia, nausea, and vomiting.
Blood and lymphatic system disorders: Changes in the number of white blood cells and platelets such as agranulocytosis (decrease in the number of granulocytes), leukopenia (decrease in the number of leukocytes), methemoglobinemia (presence of hemoglobin in the blood), neutropenia (decrease in the number of neutrophils), pancytopenia (deficiency of all cellular elements in the blood), thrombocytopenia (decrease in the number of platelets); thrombocytopenic purpura (small purple-red marks in the skin or other tissue caused by low number of platelets).
Immune system disorders: Allergic reactions (some are life-threatening) which may cause difficulty swallowing, unexplained wheezing, shortness of breath or difficulty in breathing, skin rash, hives, or angioedema (swelling of face, tongue or throat); proneness to infections.
Metabolism and nutrition disorders: Loss of appetite, sudden weight loss.
Vascular disorders: Unusual bleeding or bruising.
Respiratory, thoracic, and mediastinal disorders: Runny nose.
Gastrointestinal disorders: Minor stomach and intestinal disturbances, mouth ulcers, sore throat.
Skin and subcutaneous tissue disorder: Serious skin reactions (i.e., Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis) which may include symptoms such as skin reddening, blisters, rash, skin lesions, and peeling of the upper surface of the skin.
Hepatobiliary disorders: Chronic hepatic necrosis (death of liver tissues) in prolonged use, liver dysfunction, yellowing of eyes and skin.
Renal and urinary disorders: Kidney toxicity, papillary necrosis.
General disorders and administration site conditions: Fatigue or unusual tiredness.
Investigations: Slight elevations in transaminase levels.
 

Drug Interactions

Do not use with any other medicine containing paracetamol (prescription or nonprescription). If the patient is not sure whether a medicine contains paracetamol, ask a doctor.
Chronic intake of alcohol may increase the risk of paracetamol-induced liver toxicity. Acute intake of alcohol may diminish the ability of the body to metabolize large doses of paracetamol.
The absorption of paracetamol may be accelerated by metoclopramide or domperidone and reduced by cholestyramine.
Medicines which stimulate the enzymes responsible for the metabolic activation of paracetamol such as medicines for convulsion (e.g., phenobarbital), depression (e.g., tricyclic antidepressants), and oral contraceptives may reduce the efficacy of paracetamol and increase susceptibility to the harmful effects to the liver.
Phenothiazines (medicines for serious mental and emotional disorder) may increase the risk of severe hypothermia (abnormally low body temperature).
An increase in the International Normalized Ratio (INR), which may serve as a sign of increased risk for bleeding, may be observed when using paracetamol and warfarin (a blood thinning medicine) at the same time. Paracetamol increases the blood thinning effect of warfarin and other coumarins.
Tell the doctor if the patient is taking other medicines (especially other paracetamol-containing medicines), including vitamins, supplements, and herbal medicines.
 

Storage

Store at temperatures not exceeding 30°C.
For oral drops and suspension: Do not refrigerate.
 

Action

These products contain paracetamol, a fever reducer and pain reliever.
 

MedsGo Class

Analgesics (Non-Opioid) & Antipyretics

Features

Brand
Biogesic
Full Details
Dosage Strength
100mg /ml
Drug Ingredients
  • Paracetamol
Drug Packaging
Suspension (Oral Drops) 15ml
Generic Name
Paracetamol
Drug Flavor
Orange
Dosage Form
Suspension (Oral Drops)
Registration Number
DRHR-1167
Drug Classification
Household Remedy (HR)
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