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RITEMED Paracetamol 120mg / 5mL Syrup 60mL Lemon

NONRXDRUG-HRP-003-02
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Features

Brand
RiteMed
Full Details
Dosage Strength
120mg / 5ml
Drug Ingredients
  • Paracetamol
Drug Packaging
Syrup 60ml
Generic Name
Paracetamol
Drug Flavor
Lemon
Dosage Form
Syrup
Registration Number
HRP-003-02
Drug Classification
Household Remedy (HR)
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Description

Indications/Uses

Tablet: For the relief of minor aches and pains such as headache, backache, menstrual cramps, muscular aches, minor arthritis pain, toothache, and pain associated with the common cold and flu; for fever reduction.
120 mg/5 mL Syrup: Used in the symptomatic relief of pain and fever.
250 mg/5 mL Syrup: For the treatment of minor febrile conditions, reduction of temperature and relief of headache and joint muscle pains.
 

Dosage/Direction for Use

Tablet: Adults and Children 12 Years Old and Above: 1 to 2 tablets every 4 to 6 hours, as needed for pain and/or fever, or, as directed by a doctor.
Do not take more than 4 g (8 tablets) of paracetamol in each 24-hour period.
Missed Dose: If a dose is missed, give the next dose if still needed for pain and/or fever and the subsequent dose every 4 to 6 hours thereafter.
Do not double the dose.
120 mg/5 mL Syrup: 6 to 12 Years Old: 10 mL (2 teaspoonfuls) to 20 mL (4 teaspoonfuls), 1 to 5 Years Old: 5 mL (1 teaspoonful) to 10 mL (2 teaspoonfuls).
To be taken 3 to 4 times a day. Or, as prescribed by the physician.
250 mg/5 mL Syrup: Children: 7 to 12 Years: 5 mL (1 teaspoonful) to 10 mL (2 teaspoonfuls), 2 to 6 Years: 2.5 mL (1/2 teaspoon) to 5 mL (1 teaspoonful).
To be taken 3 to 4 times a day, or as prescribed by the physician.
Adults: 15 mL (1 tablespoonful) 3 to 4 times a day or, as prescribed by the physician.
 

Overdosage

Tablet: Sign/Symptoms: Overdosage of paracetamol usually involves 4 phases with the following signs and symptoms: Eating disorder, nausea, vomiting, malaise, and excessive sweating. Right upper abdominal pain or tenderness, liver enlargement which may be characterized by abdominal discomfort of "feeling full", elevated bilirubin and liver enzyme concentrations, prolongation of prothrombin time, and occasionally decreased urine output. Eating disorder, nausea, vomiting, and malaise recur and signs of liver (e.g., jaundice) and possibly kidney failure. Recovery or progression to fatal complete liver failure.
What to do if the patient has taken more than the recommended dosage: If more than the recommended dosage has been given, consult a doctor or contact a Poison Control Center right away. Quick medical attention is important for adults as well as for children even if any signs or symptoms were not notice.
 

Administration

May be taken with or without food.
 

Contraindications

Tablet: If the patient is allergic to paracetamol or any ingredient in the product.
Avoid long-term use of paracetamol in patients with anemia or with heart, lung, kidney or liver disease.
Syrup: Known hypersensitivity to paracetamol. Long term use in patients with anemia or with cardiac, pulmonary, renal or hepatic disease is also contraindicated.
250 mg/5 mL Syrup: Patients with ulceration or inflammation of gastrointestinal tract.
 

Warnings

Syrup: If fever persists for more than 3 days or if pain continues for more than 5 days, physician should be consulted.
 

Special Precautions

Tablet: Care That Should Be Taken When Taking This Medicine: Liver Warning: This product contains paracetamol. Severe liver damage may occur if: An adult or child 12 years old and above takes more than 4 g (8 tablets) in 24 hours, which is the maximum daily amount; taken with other medicines containing paracetamol (or acetaminophen); an adult has 3 or more alcoholic drinks everyday while using this product.
Ask a doctor before use if the patient has liver disease.
Ask a doctor before use if the patient is taking warfarin, a blood thinning medicine.
If the patient is pregnant or breastfeeding, consult the doctor before use.
Stop Use and Ask a Doctor If: New symptoms occur, symptoms do not get better, headache is persistent, pain gets worse or lasts more than 10 days, fever gets worse or lasts more than 3 days.
Syrup: Paracetamol should be given with caution to patients with impaired kidney or liver functions as well as to patients taking other drugs that affect the liver and to patients with alcohol dependence.
 

Adverse Reactions

Tablet: Paracetamol, when taken within the recommended dose and duration of treatment, has low incidence of side effects.
Skin rashes, hypersensitivity reactions, changes in the number of white blood cells and platelets, and minor stomach and intestinal disturbances have been reported.
Syrup: When taken in recommended dose, paracetamol is usually free from side effects. Skin reactions, e.g., urticaria have been described rarely. Overdosage with paracetamol can result in severe liver damage and sometimes acute renal tubular necrosis. Prompt treatment with acetylcysteine or methionine is essential.
 

Drug Interactions

Tablet: The speed of absorption of paracetamol may be accelerated by metoclopramide or domperidone and reduced by cholestyramine.
Medicines which stimulate the enzymes responsible for the metabolic activation of paracetamol such as medicines for convulsion (e.g., phenobarbital) may increase susceptibility to harmful effects to the liver.
Warfarin, a blood thinning medicine; an increase in the International Normalized Ratio (INR), which may serve as a sign of increased risk for bleeding, may be observed when using paracetamol and warfarin at the same time. Paracetamol increases the anticoagulation effect of warfarin.
Syrup: May interact with alcohol, oral anticoagulants, chloramphenicol, aspirin, phenobarbital, liver enzyme inducer, hepatotoxic agents.
 

Storage

Tablet: Do not store above 30°C.
Syrup: Store at temperatures not exceeding 30°C. Protect from light. Always keep bottle tightly closed.
 

Action

120 mg/5 mL Syrup: Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentration occurring about 30 minutes to 2 hours after ingestion. It is metabolized in the liver and excreted in the urine mainly as glucuronide and sulphate metabolites of paracetamol were reduced after administration of salicylamide. The elimination half-life varies from about 1 to 4 hours. Plasma protein binding is negligible at usual therapeutic concentration but increases with increasing concentrations.
250 mg/5 mL Syrup: Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentration occurring about 10 minutes to 60 minutes after oral administration. It is metabolized in the liver and excreted in the urine mainly as glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged paracetamol. The elimination half-life varies from about 1 to 3 hours. Plasma protein binding is negligible at unusual therapeutic concentration but increases with increasing concentrations.
 

MedsGo Class

Analgesics (Non-Opioid) & Antipyretics
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