HYFER-125 Paracetamol 125mg / 5mL Oral Suspension 60mL Orange
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Features
- Paracetamol
Description
Indications/Uses
It is also used to relieve the symptoms of cold and flu.
It is also used to help reduce a fever (high temperature).
Dosage/Direction for Use
See table.
Adults and children over 16 years: Two - four 5ml spoonfuls (large end) up to 4 times a day.
Mode of Administration: For oral administration only.
It is important to shake the bottle for at least 10 seconds before use.
Administration
Contraindications
Patients with severe hepatic dysfunction.
Special Precautions
The patient may be more at risk of the side effects of paracetamol.
Adverse Reactions
Drug Interactions
Chronic alcohol intake can increase the hepatotoxicity of paracetamol overdose and may have contributed to the acute pancreatitis reported in one patient who had taken an overdose of paracetamol. Acute alcohol intake may diminish an individual's ability to metabolise large doses of paracetamol, the plasma half-life of which can be prolonged.
The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by colestyramine.
The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of paracetamol with increased risk of bleeding, occasional doses have no significant effect.
Antivirals: Regular use of Paracetamol possible reduces metabolism of Zidovudine (increased risk of neutropenia).
The use of drugs that induce hepatic microsomal enzymes such as anticonvulsants and oral contraceptives may increase the extent of metabolism of paracetamol resulting in reduced plasma concentrations of the drug and a faster elimination rate.
Caution For Usage
Storage
Shelf Life: 36 Months.