MONNAX Aluminum Hydroxide / Magnesium Hydroxide 225mg / 200mg per 5mL Suspension 120mL
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Features
- Aluminum
- Magnesium
Description
Indications/Uses
Monnax Plus: Symptomatic relief of hyperacidity associated w/ peptic ulcer, gastritis, esophagitis & dyspepsia. Antiflatulent to alleviate the symptoms of gassiness including post-op gas pain associated w/ hyperacidity. Adjunct to H2-blockers or proton pump inhibitors for rapid relief of ulcer symptoms.
Dosage/Direction for Use
Overdosage
Aluminium and magnesium are eliminated through urinary route; treatment of acute overdose consists of administration of IV Calcium Gluconate, rehydration and forced diuresis. In case of renal function deficiency, haemodialysis or peritoneal dialysis is necessary.
Administration
Contraindications
Warnings
Special Precautions
Use In Pregnancy & Lactation
Adverse Reactions
Drug Interactions
Concomitant use with quinidines may increase the serum levels of quinidine and lead to quinidine overdosage.
Aluminium-containing antacids may prevent the proper absorption of H2-antagonists, atenolol, chloroquine, cyclines, diflunisal, digoxin, diphosphonates, ethambutol, fluoroquinolones, sodium fluorine, glucocorticoids, indomethacin, isoniazid, kayexalate, ketoconazole, lincosamides, metoprolol, neuroleptics, phenothiazines, penicillamine, propranolol, iron salts.
Staggering the administration times of the interacting drug and the antacid by at least 2 hrs (4 hrs for the fluoroquinolones) will often help avoid undesirable drug interactions.
Storage
Action
Pharmacology: Pharmacodynamic: Aluminum hydroxide is a slow-acting antacid and magnesium hydroxide is fast acting. The 2 are frequently combined in antacid mixtures. Aluminum hydroxide on its own is astringent and may cause constipation. This effect is balanced by the effect of magnesium hydroxide, which, in common with other magnesium salts, may cause diarrhea.
Pharmacokinetic: The absorption of aluminium and magnesium from antacids is small. Aluminum hydroxide is slowly converted to aluminium chloride in the stomach. Some absorption of soluble aluminium salts occur in the gastrointestinal tract with urinary excretion. Any absorbed magnesium is likewise excreted in the urine.