Indications/Uses
For the symptomatic relief of hyperacidity associated with peptic ulcer, gastritis, esophagitis and dyspepsia.
As an antiflatulent to alleviate the symptoms of gassiness, including postoperative gas pain, associated with hyperacidity.
As adjunct to H2-blockers or proton pump inhibitors for the rapid relief of ulcer symptoms.
As an antiflatulent to alleviate the symptoms of gassiness, including postoperative gas pain, associated with hyperacidity.
As adjunct to H2-blockers or proton pump inhibitors for the rapid relief of ulcer symptoms.
Dosage/Direction for Use
Tablet may be chewed then swallowed without water or swallowed whole with water.
Recommended Adult Dose: 1 to 2 tablets to be taken one hour after each meal and at bedtime.
Or, as prescribed by a doctor.
If taken more than the recommended dosage, consult a doctor.
Missed Dose: If the patient misses a dose, just give the next dose and the subsequent doses at the recommended time or schedule.
Do not double the dose unless recommended by a doctor.
Recommended Adult Dose: 1 to 2 tablets to be taken one hour after each meal and at bedtime.
Or, as prescribed by a doctor.
If taken more than the recommended dosage, consult a doctor.
Missed Dose: If the patient misses a dose, just give the next dose and the subsequent doses at the recommended time or schedule.
Do not double the dose unless recommended by a doctor.
Overdosage
Signs and Symptoms of Overdosage: Aluminum Hydroxide may accumulate in bones, lungs and nerve tissues in patients with kidney failure. Large doses or chronic use of Aluminum may also cause phosphorus depletion which is characterized by anorexia, malaise, and muscle weakness. Prolonged use may cause kidney stones, osteomalacia (softening of the bones) and osteoporosis.
Hypotension, nausea, vomiting, ECG change, respiratory or mental depression, and coma have also been reported with large doses of Magnesium in patients with severe kidney disease.
Simeticone overdosage is not expected to cause any clinically important effects.
If the patient has taken more than the recommended dosage, consult a doctor.
Hypotension, nausea, vomiting, ECG change, respiratory or mental depression, and coma have also been reported with large doses of Magnesium in patients with severe kidney disease.
Simeticone overdosage is not expected to cause any clinically important effects.
If the patient has taken more than the recommended dosage, consult a doctor.
Administration
Should be taken on an empty stomach: Take 1 hr after each meal & at bedtime. Swallow whole w/ water. May be chewed then swallow w/o water.
Contraindications
Allergy to any ingredient in the product.
If the patient has: Kidney disease, Intestinal obstruction, Appendicitis, Fecal impaction, Gastric outlet obstruction, Constipation, Phosphate depletion and low serum phosphate, Osteomalacia (softening of bones).
If the patient has: Kidney disease, Intestinal obstruction, Appendicitis, Fecal impaction, Gastric outlet obstruction, Constipation, Phosphate depletion and low serum phosphate, Osteomalacia (softening of bones).
Special Precautions
Patients with advanced kidney disease are at risk of Aluminum and Magnesium accumulation and toxicity. Do not use these products in such patients.
Phenylketonurics: This product contains Phenylalanine as one of the metabolites of Aspartame.
Consult the doctor: Ask a doctor before use if the patient is: Pregnant or breastfeeding.
Taking other medicines; antacids may interact with certain medicines.
Stop use and ask a doctor if the patient needs to take this product for more than 14 days.
Phenylketonurics: This product contains Phenylalanine as one of the metabolites of Aspartame.
Consult the doctor: Ask a doctor before use if the patient is: Pregnant or breastfeeding.
Taking other medicines; antacids may interact with certain medicines.
Stop use and ask a doctor if the patient needs to take this product for more than 14 days.
Use In Pregnancy & Lactation
Ask a doctor before use if the patient is pregnant or breastfeeding.
Adverse Reactions
The combination of Aluminum Hydroxide and Magnesium Hydroxide balances the side effects of diarrhea from Magnesium Hydroxide and constipation from Aluminum Hydroxide.
Excessive doses of Aluminum Hydroxide and Magnesium Hydroxide may result in high Aluminum and Magnesium levels in the blood in patients with kidney impairment.
Excessive doses of Aluminum Hydroxide and Magnesium Hydroxide may result in high Aluminum and Magnesium levels in the blood in patients with kidney impairment.
Drug Interactions
Antacids decrease the absorption of Tetracycline and Iron. Take Tetracycline 1 hour before or 2 hours after antacids and 2 hours before or 3 hours after Iron-containing preparations.
Antacids may decrease the absorption of orally administered Digoxin, or Indomethacin, Isoniazid, Quinolones (e.g., Ciprofloxacin, Ofloxacin), Ketoconazole. Doses of these drugs should be spaced as far apart as possible from doses of antacids.
Antacid-induced changes in urine pH increase urinary excretion and decrease blood concentration of salicylates such as Aspirin.
Antacid-induced increases in urine pH may decrease excretion of weakly basic drugs (e.g., Quinidine, Chlorpromazine, Propranolol, Diazepam) and increase excretion of weakly acidic drugs (e.g., Phenytoin, Pentobarbital, Warfarin).
Aluminum-Magnesium antacid combination is reported to increase the absorption of Dicumarol, Diazepam and Pseudoephedrine.
Magnesium and Aluminum Hydroxide administration may decrease the rate of Chlordiazepoxide absorption.
Antacids reduce the bioavailability of bisphosphonates (e.g., Alendronate, Etidronate, Risedronate).
Antacids may decrease the absorption of orally administered Digoxin, or Indomethacin, Isoniazid, Quinolones (e.g., Ciprofloxacin, Ofloxacin), Ketoconazole. Doses of these drugs should be spaced as far apart as possible from doses of antacids.
Antacid-induced changes in urine pH increase urinary excretion and decrease blood concentration of salicylates such as Aspirin.
Antacid-induced increases in urine pH may decrease excretion of weakly basic drugs (e.g., Quinidine, Chlorpromazine, Propranolol, Diazepam) and increase excretion of weakly acidic drugs (e.g., Phenytoin, Pentobarbital, Warfarin).
Aluminum-Magnesium antacid combination is reported to increase the absorption of Dicumarol, Diazepam and Pseudoephedrine.
Magnesium and Aluminum Hydroxide administration may decrease the rate of Chlordiazepoxide absorption.
Antacids reduce the bioavailability of bisphosphonates (e.g., Alendronate, Etidronate, Risedronate).
Storage
Store at temperatures not exceeding 30°C.
Action
This product contains a combination of antacids, Aluminum Hydroxide and Magnesium Hydroxide, which effectively increase gastric pH by neutralizing the acid produced in the stomach.
This product also contains Simeticone, a water-repellant with low surface tension used to relieve bloating and gassiness by causing small bubbles to coalesce to large bubbles, which are passed more easily.
This product also contains Simeticone, a water-repellant with low surface tension used to relieve bloating and gassiness by causing small bubbles to coalesce to large bubbles, which are passed more easily.
MedsGo Class
Antacids, Antireflux Agents & Antiulcerants
Features
Brand
Kremil- S
Full Details
Dosage Strength
178 mg / 233 mg / 30 mg
Drug Ingredients
- Aluminum
- Magnesium
- Simethicone
Drug Packaging
Chewable Tablet 4's
Generic Name
Aluminum / Magnesium / Simethicone
Dosage Form
Chewable Tablet
Registration Number
DR-XY29478
Drug Classification
Over-The-Counter (OTC)
View all variations as list
| CODE | Dosage Strength | Drug Packaging | Availability | Price | ||
|---|---|---|---|---|---|---|
|
NONRXDRUG-DR-XY29478-1pc
|
In stock
|
₱900 | |||
|
KREMIL--4RRFO9
|
In stock
|
₱3600 |