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GEL-MALICID Aluminum Hydroxide / Magnesium Hydroxide 200mg / 100mg Tablet 1's

NONRXDRUG-DRP-1112-1pc
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Features

Brand
Gel-Malicid
Full Details
Dosage Strength
200 mg / 100 mg
Drug Ingredients
  • Aluminum
  • Magnesium
Drug Packaging
Tablet 1's
Generic Name
Aluminum Hydroxide / Magnesium Hydroxide
Dosage Form
Tablet
Registration Number
DRP-1112
Drug Classification
Over-The-Counter (OTC)
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Description

Indications/Uses

For the symptomatic relief of hyperacidity associated with peptic ulcer, gastritis, esophagitis, and dyspepsia.
As adjunct to H2-blockers or proton pump inhibitors for the rapid relief of ulcer symptoms.
 

Dosage/Direction for Use

Recommended Adult Dose: 1 to 2 tablets one hour after each meal and at bedtime.
Or, as prescribed by a physician.
What to do if the patient misses a dose: If the patient misses a dose, just give the next dose and the subsequent doses at the recommended time or schedule.
Do not double the dose unless recommended by a doctor.
 

Overdosage

Signs and symptoms: Aluminum hydroxide may accumulate in bones, lungs and nerve tissues in patients with kidney failure. Large doses of chronic use of aluminum may also cause phosphorus depletion which is characterized by anorexia, malaise and muscle weakness. Prolonged use may cause kidney stones, osteomalacia (softening of bones) and osteoporosis.
Hypotension, nausea, vomiting, ECG change, respiratory and mental depression, and coma have also been reported with large dose of magnesium in patients with severe kidney disease.
What to do when the patient has taken more than the recommended dose: If the patient has taken more than the recommended dose, consult a doctor.
 

Administration

Should be taken on an empty stomach: Take 1 hr after each meal & at bedtime.
 

Contraindications

If patient is allergic to any ingredient in this product.
If patient has: Kidney disease; Intestinal obstruction; Appendicitis; Fecal impaction (solid, dry stool stuck in the rectum); Gastric outlet obstruction (narrowing of the opening from the stomach into the small intestine); Constipation; Phosphate depletion; Osteomalacia (softening of bones).
 

Special Precautions

Patients with advanced kidney disease are at risk of aluminum and magnesium accumulation and toxicity. Do not use this product in such patients.
Aluminum hydroxide maybe unsafe in patients with porphyria undergoing hemodialysis.
When to consult a doctor: Ask a doctor before use if the patient is: Pregnant or breastfeeding; taking other medicines; antacids may interact with certain medicines.
Stop use and ask a doctor if the patient needs to take this product for more than 14 days.
 

Use In Pregnancy & Lactation

Ask a doctor before use if the patient is: Pregnant or breastfeeding.
 

Adverse Reactions

The combination of aluminum hydroxide and magnesium hydroxide balances the side effects of diarrhea from magnesium hydroxide and constipation from aluminum hydroxide.
Excessive doses of aluminum hydroxide and magnesium hydroxide may result in high aluminum and magnesium levels in the blood in patients with kidney impairment.
 

Drug Interactions

Lowering the acidity of stomach contents decreases the absorption of iron, ketoconazole and tetracyclines. The absorption of tetracyclines is further reduced by its chelation with aluminum and magnesium ions. Tetracycline doses should be given 1 to 2 hours before or after doses of antacids.
Concurrent administration of antacids and orally-administered angiotensin-converting enzyme (ACE) inhibitors, digoxin, indomethacin, or iron salts may decrease the absorption of these drugs. Doses of these drugs should be spaced as far as possible from doses of antacids.
Antacid-induced increases in urine pH increase urinary excretion and decrease blood concentration of salicylates.
Antacid-induced increase in urinary pH may decrease excretion of weakly basic drugs and increase excretion of weakly acidic drugs.
Administration of a magnesium and aluminum hydroxide preparation with chlordiazepoxide decreases the rate of chlordiazepoxide absorption.
Antacids reduce the absorption of biphosphonates, (e.g. alendronate, etidronate, risedronate).
Interaction can be minimized by giving Aluminum hydroxide + Magnesium hydroxide and any other medication 2 to 3 hours apart.
 

Storage

Store at temperatures not exceeding 30°C. Protect from light.
 

Action

This product contains a combination of antacids, aluminum hydroxide and magnesium hydroxide, which effectively increase gastric pH by neutralizing the acid produced in the stomach.
 

MedsGo Class

Antacids, Antireflux Agents & Antiulcerants
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