Indications/Uses
These medicines are used for the relief of clogged nose, runny nose, itchy, watery eyes, and sneezing associated with the common cold, upper airway cough syndrome (postnasal drip syndrome), allergic rhinitis, and other minor respiratory tract infections. They also help decongest sinus openings and passages.
Dosage/Direction for Use
These medicines should be taken orally (by mouth). (See table.)
Missed Dose: If the patient misses a dose, just take the next dose if still needed for the condition being treated, and the subsequent doses at the recommended time or schedule (i.e., every 6 hrs).
Do not double the dose.
Do not double the dose.
Overdosage
Phenylephrine HCl: Increased blood pressure, headache, seizures, palpitation, paresthesia (sensation of tingling, pricking or numbness of the skin), vomiting, cerebral hemorrhage (bleeding from a ruptured blood vessel in the brain).
Chlorphenamine maleate: Extreme sleepiness or prolonged drowsiness, weakness, hallucination, convulsion, agitation, irritability, tachycardia (fast heart rate), coma.
If patient has taken more than the recommended dosage, consult a doctor.
Chlorphenamine maleate: Extreme sleepiness or prolonged drowsiness, weakness, hallucination, convulsion, agitation, irritability, tachycardia (fast heart rate), coma.
If patient has taken more than the recommended dosage, consult a doctor.
Administration
May be taken with or without food.
Contraindications
If patient is allergic to any ingredient in the product.
If patient has high blood pressure or severe heart disease unless recommended by a doctor.
If patient is pregnancy or breastfeeding.
If patient has high blood pressure or severe heart disease unless recommended by a doctor.
If patient is pregnancy or breastfeeding.
Special Precautions
May cause drowsiness; patients should observe caution while driving or performing other tasks requiring alertness.
Before taking this medication, tell the doctor if patient has: high blood pressure or any type of heart problems; glaucoma; thyroid problems; diabetes; an enlarged prostate, bladder problems or difficulty urinating.
If symptoms do not improve or new symptoms appear.
Before taking this medication, tell the doctor if patient has: high blood pressure or any type of heart problems; glaucoma; thyroid problems; diabetes; an enlarged prostate, bladder problems or difficulty urinating.
If symptoms do not improve or new symptoms appear.
Use In Pregnancy & Lactation
Contraindicated during pregnancy & lactation.
Adverse Reactions
Phenylephrine HCl may cause tremors (muscle shaking), restlessness, anxiety (feeling of uneasiness), insomnia/sleeplessness, nervousness, dizziness, increased blood pressure, palpitation (rapid and irregular heart beat), arrhythmia (irregular heart beat), weakness, respiratory distress (noisy, congested breathing) and pallor (pale skin color).
Chlorphenamine maleate may cause sleepiness and drowsiness. Other undesirable effects include muscle weakness, gastrointestinal discomfort, nausea, vomiting, diarrhea or constipation, dryness of the mouth, nose and throat, difficulty urinating, ringing in the ears, visual disturbance, blurred vision, insomnia/sleeplessness, tremors, nervousness, irritability, chest tightness, increased or decreased blood pressure and headache.
Chlorphenamine maleate may cause sleepiness and drowsiness. Other undesirable effects include muscle weakness, gastrointestinal discomfort, nausea, vomiting, diarrhea or constipation, dryness of the mouth, nose and throat, difficulty urinating, ringing in the ears, visual disturbance, blurred vision, insomnia/sleeplessness, tremors, nervousness, irritability, chest tightness, increased or decreased blood pressure and headache.
Drug Interactions
Do not use this product together with sympathomimetic agents (e.g., Epinephrine) and general anesthetics (e.g., Halothane, etc.) because of the possibility for increased toxicity.
Concurrent administration with antidepressants (e.g., Amitriptyline, Imipramine, Sertraline, Moclobemide) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic-blocking agent (e.g., Phenothiazine drugs, Phentolamine, Propranolol, etc.) before the administration of this product may decrease the effect of phenylephrine.
Tell the doctor about other medicines the child is taking, especially other medicines for cough, cold or allergy.
Concurrent administration with antidepressants (e.g., Amitriptyline, Imipramine, Sertraline, Moclobemide) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic-blocking agent (e.g., Phenothiazine drugs, Phentolamine, Propranolol, etc.) before the administration of this product may decrease the effect of phenylephrine.
Tell the doctor about other medicines the child is taking, especially other medicines for cough, cold or allergy.
Storage
Store at temperatures not exceeding 30°C.
Action
These medicines contain Phenylephrine HCl and Chlorphenamine maleate.
Phenylephrine HCl, a nasal decongestant, clears obstructed air passages and nasal sinuses due to congestion making breathing easier. It also reduces postnasal drip.
Chlorphenamine maleate, an anti-allergy, relieves symptoms of allergy such as runny nose, sneezing, and itchy, watery eyes.
Phenylephrine HCl, a nasal decongestant, clears obstructed air passages and nasal sinuses due to congestion making breathing easier. It also reduces postnasal drip.
Chlorphenamine maleate, an anti-allergy, relieves symptoms of allergy such as runny nose, sneezing, and itchy, watery eyes.
MedsGo Class
Cough & Cold Preparations
Features
Brand
Disudrin
Full Details
Dosage Strength
2.5mg / 500mcg /ml Syrup
Drug Ingredients
- Chlorphenamine Maleate
- Phenylephrine
Drug Packaging
Syrup (Oral Drops) 10ml
Generic Name
Phenylephrine Hydrochloride / Chlorphenamine Maleate
Drug Flavor
Orange
Dosage Form
Syrup (Oral Drops)
Registration Number
DR-XY33744
Drug Classification
Over-The-Counter (OTC)