BIOFLU Phenylephrine Hydrochloride / Chlorphenamine Maleate / Paracetamol 10mg / 2mg / 500mg Tablet 1's
Indications/Uses
Dosage/Direction for Use
Missed Dose: If the patient missed a dose, just take the next dose if still needed for the condition being treated, and the subsequent doses at the recommended time or schedule (i.e., every 6 hours).
Do not double the dose.
Overdosage
Chlorphenamine Maleate: Extreme sleepiness or prolonged drowsiness, convulsion, weakness, agitation, hallucination, irritability, tachycardia, and coma.
Paracetamol: Overdosage of Paracetamol usually involves 4 phases with the following signs and symptoms: Eating disorder, nausea, vomiting, malaise, and excessive sweating.
Right upper abdominal pain or tenderness, liver enlargement which may be characterized by abdominal discomfort of "feeling full", elevated bilirubin and liver enzyme concentrations, prolongation of prothrombin time, and occasionally decreased urine output.
Eating disorder, nausea, vomiting, and malaise recur and signs of liver (e.g., jaundice) and possibly kidney failure.
Recovery or progression to fatal complete liver failure.
Administration
Contraindications
If the patient has a history or is suffering from stomach ulcers, bleeding or other stomach problems.
If the patient has high blood pressure or severe heart disease unless recommended by a doctor.
If the patient has anemia, kidney or liver disease unless recommended by a doctor.
If the patient is pregnant or breastfeeding.
Special Precautions
Allergy Alert: Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include: Hives, (elevated, whitish or reddish patches on the skin with severe itching or pricking sensations); shock (anaphylactic), a hypersensitivity reaction resulting in generalized skin lesions and itchiness, followed by low blood pressure and often accompanied by difficulty in breathing; facial swelling; skin reddening; skin rash and skin blisters; asthma (wheezing). If an allergic reaction occurs, stop use and seek medical help right away.
Use In Pregnancy & Lactation
Adverse Reactions
Chlorphenamine Maleate may cause sleepiness and drowsiness. Other undesirable effects include muscle weakness, gastrointestinal discomfort, nausea, vomiting, diarrhea or constipation, dryness of the mouth, nose, and throat, difficulty urinating, ringing in the ears, visual disturbance, blurred vision, insomnia/sleeplessness, tremor, nervousness, irritability, chest tightness, increased or decreased blood pressure, and headache.
Paracetamol, when taken within the recommended dose and duration of treatment, has low incidence of side effects. Skin rashes, hypersensitivity reactions, changes in the number of white blood cells and platelets, and minor stomach and intestinal disturbances have been reported.
Drug Interactions
Concurrent administration with medicines for depression (e.g., Amitriptyline, Imipramine, Sertraline, Moclobemide, etc.) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic-blocking agent (e.g., Phenothiazine drugs, Phentolamine, Propranolol, etc.) before the administration of these products may decrease the effect of Phenylephrine.
The absorption of Paracetamol may be accelerated by Metoclopramide or Domperidone and absorption reduced by Cholestyramine.
Medicines which stimulate the enzymes responsible for the metabolic activation of Paracetamol such as medicines for convulsion (e.g., Phenobarbital, etc.) may increase susceptibility to the harmful effects to the liver.
Warfarin, a blood thinning medicine; an increase in the International Normalized Ratio (INR), which may serve as a sign of increased risk of bleeding, may be observed when using Paracetamol and Warfarin at the same time.
Paracetamol increases the anticoagulation effect of Warfarin.
Ibuprofen may interfere with the anti-platelet activity of aspirin, thus limiting aspirin's cardioprotective effect.
Phenylbutazone, indomethacin, salicylates (e.g., aspirin), and other NSAIDs (e.g., mefenamic acid, naproxen, diclofenac, ketoprofen), including COX-2 inhibitors (e.g., celecoxib, etoricoxib), increase the risk of stomach and intestinal bleeding in patients receiving ibuprofen.
When taken with blood thinning (anticoagulant) medicines (e.g., warfarin, dicumarol) or together with thrombolytic agents (e.g., streptokinase), ibuprofen may cause stomach and intestinal bleeding.
Tell the doctor about other medicines patient is taking, especially for cough, cold, allergy, pain or fever.
Storage
Action
MedsGo Class
Features
- Chlorphenamine Maleate
- Paracetamol
- Phenylephrine Hcl