WOLVIT Biotin 5mg Film-Coated Tablet 30's
NONRXDRUG-DR-XY45188
Discreet Packaging
FDA-registered Products
FDA-licensed Pharmacies
Indications/Uses
For the prevention and treatment of biotin deficiency.
Dosage/Direction for Use
Older patients may be given 10 mg daily.
The usual maintenance dose ranges from 10 to 50 mg daily, though up to 100 mg daily may be needed.
In malabsorption syndrome, the recommended dose is 10 mg per day. In adults and children with symptoms of biotin deficiency, the recommended dose is 5-20 mg per day.
In case of biotinidase deficiency in adults and children, the recommended dose is 5-10 mg per day.
In case of genetically determined biotin-dependent enzyme insufficiency (multiple deficit of carboxylase) the recommended dose is 20 mg per day. The medicine can be used for a long time and the usual treatment period is about one month.
What to do if the patient missed a dose: If the patient missed a treatment with WOLVIT Tablet, instruct the patient to take it as soon as remembered.
Do not use the tablet twice to make up for a missed treatment. For further questions on the use of this medicine, ask the doctor or pharmacist.
The usual maintenance dose ranges from 10 to 50 mg daily, though up to 100 mg daily may be needed.
In malabsorption syndrome, the recommended dose is 10 mg per day. In adults and children with symptoms of biotin deficiency, the recommended dose is 5-20 mg per day.
In case of biotinidase deficiency in adults and children, the recommended dose is 5-10 mg per day.
In case of genetically determined biotin-dependent enzyme insufficiency (multiple deficit of carboxylase) the recommended dose is 20 mg per day. The medicine can be used for a long time and the usual treatment period is about one month.
What to do if the patient missed a dose: If the patient missed a treatment with WOLVIT Tablet, instruct the patient to take it as soon as remembered.
Do not use the tablet twice to make up for a missed treatment. For further questions on the use of this medicine, ask the doctor or pharmacist.
Overdosage
Signs and Symptoms of Overdose: No cases of overdose have been reported till date, even with administration of high doses.
What to do when the patient has taken more than the recommended dosage: In the event of overdose, supportive and symptomatic measures should be carried out.
What to do when the patient has taken more than the recommended dosage: In the event of overdose, supportive and symptomatic measures should be carried out.
Administration
Should be taken on an empty stomach: Take before meals w/ small portion of water.
Contraindications
Hypersensitivity to biotin or other components of the product and children below 12 years old.
Special Precautions
Care that should be taken when taking this medicine: Do not alter the treatment duration prescribed by the doctor; if discontinued, its efficacy may be reduced.
Due to the good tolerance of biotin, treatment can be prolonged for a long period of time.
Due to the good tolerance of biotin, treatment can be prolonged for a long period of time.
Adverse Reactions
The following have been reported: Immune System Disorders: Possible allergic reactions in individual intolerant to biotin, which can be exhibited as a chest pain, shortness of breath, urticaria, appearance of skin rash.
Drug Interactions
If biotin is used concurrently with anticonvulsant products, the plasma levels concentration of biotin may be reduced as a result of elimination with urine.
Valproic acid lowers the activity of biotinidase, which reduces mitochondrial activity in liver.
The raw eggs contain the protein-avidin, which interacts with biotin, so it is necessary to avoid concomitant administration. Administration of a large quantity of raw eggs over 2-3 weeks can cause biotin deficiency. Pantothenic acid in high doses competes with biotin, therefore their concomitant administration should be avoided.
Interference with clinical laboratory tests: Biotin may interfere with laboratory tests that are based on a biotin/streptavidin interaction, leading to either falsely decreased or falsely increased test results, depending on the assay. The risk of interference is higher in children and patients with renal impairment and increases with higher doses. When interpreting results of laboratory tests, possible biotin interference has to be taken into consideration, especially if a lack of coherence with the clinical presentation is observed (e.g. thyroid test results mimicking Graves' disease in asymptomatic patients taking biotin or false negative troponin test results in patients with myocardial infarction taking biotin). Alternative tests not susceptible to biotin interference should be used, if available, in cases where interference is suspected. The laboratory personnel should be consulted when ordering laboratory tests in patients taking biotin.
Valproic acid lowers the activity of biotinidase, which reduces mitochondrial activity in liver.
The raw eggs contain the protein-avidin, which interacts with biotin, so it is necessary to avoid concomitant administration. Administration of a large quantity of raw eggs over 2-3 weeks can cause biotin deficiency. Pantothenic acid in high doses competes with biotin, therefore their concomitant administration should be avoided.
Interference with clinical laboratory tests: Biotin may interfere with laboratory tests that are based on a biotin/streptavidin interaction, leading to either falsely decreased or falsely increased test results, depending on the assay. The risk of interference is higher in children and patients with renal impairment and increases with higher doses. When interpreting results of laboratory tests, possible biotin interference has to be taken into consideration, especially if a lack of coherence with the clinical presentation is observed (e.g. thyroid test results mimicking Graves' disease in asymptomatic patients taking biotin or false negative troponin test results in patients with myocardial infarction taking biotin). Alternative tests not susceptible to biotin interference should be used, if available, in cases where interference is suspected. The laboratory personnel should be consulted when ordering laboratory tests in patients taking biotin.
Storage
Store at temperatures not exceeding 30°C.
MedsGo Class
Vitamins &/or Minerals
Features
Brand
Wolvit
Full Details
Dosage Strength
5mg
Drug Ingredients
- Biotin
Drug Packaging
Film-Coated Tablet 30's
Generic Name
Biotin
Dosage Form
Film-Coated Tablet
Registration Number
DR-XY45188
Drug Classification
Over-The-Counter (OTC)
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