MULTIVENT Salbutamol / Ipratropium Bromide 2.5mg / 500mcg Solution for Inhalation 2.5mL 1's
RXDRUG-DRP-4504-01
Discreet Packaging
FDA-registered Products
FDA-licensed Pharmacies
Indications/Uses
Adjunct treatment to anti-inflammatory therapy and bronchodilators in asthma to prevent exacerbations; maintenance treatment of chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema.
Dosage/Direction for Use
1 nebule 3-4 times a day. The dosage should be adapted to the individual requirements of the patient.
Overdosage
Symptoms: The effects of overdosage are expected to be primarily related to salbutamol because acute overdosage with ipratropium bromide is unlikely as it is not well absorbed systematically after inhalation or oral administration. Hypokalemia may occur following overdosage. Serum potassium levels should be monitored. Manifestations of overdosage with salbutamol may include angina pain, hypertension, hypokalemia and tachycardia.
Treatment: The preferred antidote for overdosage with salbutamol is a cardioselective β-blocking agent but due care and attention should be taken while administering these drugs in patients with a history of bronchospasm.
Treatment: The preferred antidote for overdosage with salbutamol is a cardioselective β-blocking agent but due care and attention should be taken while administering these drugs in patients with a history of bronchospasm.
Contraindications
Hypersensitivity to atropine and its derivatives or to any of the component of Multivent, soya lecithin or related food products eg, soybean and peanut.
Adverse Reactions
Tremor, nervousness, tachycardia, dizziness, headache, hypokalemia, dry mouth, throat irritation, urinary retention, nausea & arrhythmia.
Drug Interactions
The combination has been used concomitantly with other drugs, including sympathomimetic bronchodilators, methylxanthines and steroids, commonly used in the treatment of asthma and COPD, without adverse reactions. Caution is advised when salbutamol sulfate and ipratropium bromide is co-administered with other anticholinergic drugs, β-blockers, α-adrenergic agents, diuretics, monoamine oxidase inhibitors or tricyclic antidepressants.
Storage
Store at temperatures not exceeding 30°C.
Action
Salbutamol sulfate and ipratropium bromide is an anticholinergic (parasympatholytic) agent which acts by inhibiting vagally-mediated reflexes by antagonizing the action of acetylcholine, the transmitter agent released from the vagus nerve. Salbutamol is a relatively selective β2-adrenergic agonist whose activation leads to the increase in the intracellular adenyl cyclase, the enzyme which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3'5'-adenosine monophosphate (cAMP).
MedsGo Class
Antiasthmatic & COPD Preparations
Features
Brand
Multivent
Full Details
Dosage Strength
2.5mg / 500mcg / 2.5ml
Drug Ingredients
- Ipratropium
- Salbutamol
Drug Packaging
Solution for Inhalation 2.5ml x 1's
Generic Name
Salbutamol / Ipratropium Bromide
Dosage Form
Solution for Inhalation
Registration Number
DRP-4504-01
Drug Classification
Prescription Drug (RX)
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