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Indications/Uses
Ambroxol is used in the treatment of acute and chronic respiratory tract disorders associated with abnormal bronchial mucus secretions such as bronchitis, bronchial asthma, pneumonia and other pulmonary diseases. It is also used as an adjuvant in the treatment of sinusitis, rhinitis and other inflammatory diseases of the nasal cavity and throat when treatment of such conditions require a mucolytic.
Dosage/Direction for Use
Adult: One tablet three times daily after meals, or as prescribed by the physician.
Administration
Should be taken with food: Take immediately after meals.
Contraindications
Ambroxol should not be used in patients with history of hypersensitivity to ambroxol and bromhexine.
Ambroxol should be given cautiously to patients with history of peptic ulcer disease.
Ambroxol should be given cautiously to patients with history of peptic ulcer disease.
Special Precautions
Although no evidence has been obtained (even at high dosage levels) of teratological activity, as with any preparation, administration is not recommended during the first 3 months of pregnancy.
Use In Pregnancy & Lactation
Although no evidence has been obtained (even at high dosage levels) of teratological activity, as with any preparation, administration is not recommended during the first 3 months of pregnancy.
Adverse Reactions
Although no evidence has been obtained (even at high dosage levels) of teratological activity, as with any preparation, administration is not recommended during the first 3 months of pregnancy.
Drug Interactions
Ambroxol HCl should not be taken simultaneously with antitussives (e.g. Codeine) because phlegm which has been liquefied by Ambroxol HCl might not be expectorated.
Storage
Store at temperatures not exceeding 30°C. Protect from light.
Action
Pharmacology: Properties: AMBROXOL HCl, as a mucolytic, facilitates the expectoration of abnormal secretions present in the upper and lower respiratory tract.
AMBROXOL HCl breaks and liquefies the acid mucopolysaccharide fibers of the mucus, making it thinner and less viscid. The sputum becomes less tenacious and less sticky, thus allowing easier expectoration.
AMBROXOL stimulates mucociliary activity and enhances production of naturally occurring surfactants. It alters the structure of mucus to reduce its viscosity. Enhancement of mucociliary function and fluid secretion facilitates expectoration of mucus present in the upper and lower respiratory tract.
Pharmacokinetics: Ambroxol is rapidly and completely absorbed in the gastrointestinal tract and concentrates in the lungs. Maximum plasma level is reached within one half to three hours. Its plasma half-life is eight to twelve hours. Ambroxol HCl is metabolized mainly in the liver and eliminated thru the urine.
AMBROXOL HCl breaks and liquefies the acid mucopolysaccharide fibers of the mucus, making it thinner and less viscid. The sputum becomes less tenacious and less sticky, thus allowing easier expectoration.
AMBROXOL stimulates mucociliary activity and enhances production of naturally occurring surfactants. It alters the structure of mucus to reduce its viscosity. Enhancement of mucociliary function and fluid secretion facilitates expectoration of mucus present in the upper and lower respiratory tract.
Pharmacokinetics: Ambroxol is rapidly and completely absorbed in the gastrointestinal tract and concentrates in the lungs. Maximum plasma level is reached within one half to three hours. Its plasma half-life is eight to twelve hours. Ambroxol HCl is metabolized mainly in the liver and eliminated thru the urine.
MedsGo Class
Cough & Cold Preparations
Features
Dosage
15 mg / 5 ml
Ingredients
- Ambroxol
Packaging
Syrup 60ml
Generic Name
Ambroxol Hydrochloride
Registration Number
DR-XY25952
Classification
Prescription Drug (RX)
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