DOXOFYR Doxofylline 400mg - 1 Tablet

Indications / Uses

DOXOFYR Doxofylline 400mg is used for maintenance therapy in individuals suffering from chronic obstructive pulmonary disease (COPD), bronchial asthma, and other pulmonary diseases that involve a spastic bronchial component. As a bronchodilator, it works to help relax the muscles of the air passages in the lungs, widening them to make breathing easier. It is intended for the long-term management of these reversible airway obstructions.

Formulation / Ingredients

DOXOFYR Doxofylline 400mg contains: Doxofylline 400mg

Side Effects

DOXOFYR Doxofylline 400mg common side effects include gastrointestinal issues such as nausea, vomiting, and epigastric pain. Neurological effects like headache, irritability, and insomnia may also occur. Cardiovascular effects may present as tachycardia (rapid heart rate) or extrasystole (abnormal heart rhythm). Occasionally, tachypnea (rapid breathing), hyperglycemia, and albuminuria have been reported after administration of xanthines. Severe adverse reactions like major arrhythmias and seizures are possible in cases of overdosage and could be the first sign of toxicity.

Directions and Dosage

• Dosage for Adults: 400 mg 2 to 3 times daily. Doses as high as 1200 mg per day may be prescribed.
• Dosage for Elderly Patients: 200 mg 2 to 3 times daily.

Contraindications

This product should not be used in individuals with a known sensitivity to its components or other xanthine derivatives. It is also not recommended for use in patients who have experienced a recent acute myocardial infarction, or those with hypotension.

Use in Pregnancy and Lactation

Although animal studies suggest no harm to the fetus or reproductive capacity, limited human experience during pregnancy means use is only advised if clearly necessary. This product is generally not recommended for use by nursing mothers.

Special Precautions

• Use with caution in patients with heart conditions such as hypertension, cardiac arrhythmias, or other cardiovascular diseases.
• Should be given cautiously to individuals with a history of peptic ulceration, hyperthyroidism, porphyria, or epilepsy, as these conditions may be made worse.
• Caution is needed for those with severe hypoxemia, chronic right ventricular failure, congestive heart failure, liver dysfunction, or kidney impairment.
• Lower dosing may be necessary in patients with congestive heart failure or severe liver disease, as drug plasma levels may be prolonged.
• Dosing may also need adjustment for those with acute febrile illness or the elderly.

Is it safe to take it with other medications?

Use with other derivatives of this class of drugs should be avoided as their toxic effects are additive. Caution is advised when taking with certain antiarrhythmics, antibiotics (like macrolides), anti-flu vaccines, cimetidine, allopurinol, or oral contraceptives, as they may decrease the clearance of this medicine, potentially increasing its concentration in the blood.

How should I store it?

Store at temperatures not exceeding $30^{\circ}\text{C}$. Keep it protected from light and out of the sight and reach of children.

Used For

Bronchodilator

Age

Adults & Elderly