GOUTSAPH Colchicine 500mcg - 1 Tablet

Indications / Uses

GOUTSAPH Colchicine 500mcg is used for the management and treatment of acute gout flares, helping to relieve the pain and inflammation associated with the condition. It is also utilized for the short-term prevention of acute gout attacks, particularly when initiating therapy with other medications that lower uric acid levels. This medication is not a pain reliever in the traditional sense and does not reduce the amount of uric acid in the body.

Formulation / Ingredients

GOUTSAPH Colchicine 500mcg contains: Colchicine 500mcg

Side Effects

GOUTSAPH Colchicine 500mcg common side effects include: gastrointestinal issues such as diarrhea, nausea, vomiting, and abdominal pain or cramping. More serious, but less frequent, side effects can involve changes in blood counts, such as low white blood cell or platelet levels, which may manifest as unusual bruising, bleeding, or susceptibility to infections. Muscle problems, like pain and weakness (myopathy or rhabdomyolysis), and nerve issues, such as tingling or numbness in the hands or feet (peripheral neuropathy), are also possible, especially with long-term use.

Directions and Dosage

• Dosage for Adults (Acute Gout): Initially 1mg (2 tablets), followed by 500mcg (1 tablet) every 2 to 3 hours until pain is relieved or until gastrointestinal symptoms occur.
• Maximum Daily Dosage (Acute Gout): Do not exceed a total of 6mg during one course of treatment.
• Duration of Treatment (Acute Gout): A new course should not be repeated within 3 days.
• Dosage for Adults (Prophylaxis): 500mcg (1 tablet) 2 to 3 times daily.

Doses may need adjustment in individuals with existing kidney or liver impairment.

Contraindications

Avoid use in case of known allergy to the active ingredient. It should not be used in individuals undergoing hemodialysis or those with severe kidney impairment. Use is also not recommended for patients with existing severe liver impairment, or those with serious heart or gastrointestinal disease. Individuals with existing blood disorders should avoid this medicine.

Use in Pregnancy and Lactation

Should be used with caution during pregnancy, only if the potential benefits are judged to outweigh the risks. Due to the potential for harm, it is advised to avoid taking the product while breastfeeding.

Special Precautions

• Requires careful monitoring for signs of toxicity, especially in older people and those with kidney or liver issues.
• Caution is advised if there is a history of cardiac disease or gastrointestinal issues.
• If muscle weakness or pain occurs, stop using the product immediately.
• Avoid consuming grapefruit or grapefruit juice as it can increase the concentration of the product in the body.

Is it safe to take it with other medications?

Caution is needed when taking this product with certain other medications, especially those that affect the liver's metabolism or those that can cause muscle or nerve damage. Combining it with strong inhibitors of CYP3A4 or P-glycoprotein is generally not advised due to increased risk of serious toxicity.

How should I store it?

Store the product at temperatures not exceeding 30°C. Protect it from moisture and keep it in a secure location.

Used For

Acute gout, Prophylaxis

Age

Adults