Indications/Uses
Oral
Hyperuricaemia; Cancer therapy-induced hyperuricaemia
Hyperuricaemia; Cancer therapy-induced hyperuricaemia
Dosage/Direction for Use
Adult: In patients with chronic gout: Initially, 40 mg once daily, may increase dose to 80 mg once daily if serum uric acid is >6 mg/dL after 2 weeks. Alternatively, 80 mg once daily, may increase dose to 120 mg once daily if serum uric acid is >6 mg/dL after 2-4 weeks.
Administration
May be taken with or without food. May be taken w/o regard to antacid use.
Contraindications
Concomitant use with azathioprine, mercaptopurine..
Special Precautions
Patient with history of hypersensitivity reaction to allopurinol; major CV disease (e.g. MI, stroke, unstable angina), thyroid disorders; increased risk for urate formation (e.g. Lesch-Nyhan syndrome, malignant disease and its treatment). Organ transplant recipients. Not recommended to be started during an acute attack of gout. Use of febuxostat is restricted to patients who are intolerant to allopurinol or for whom allopurinol is contraindicated or ineffective. Not recommended for the treatment of asymptomatic or secondary hyperuricaemia. Hepatic and renal impairment. Pregnancy and lactation.
Storage
Store between 15-30°C. Protect from light.
MedsGo Class
Hyperuricemia & Gout Preparations
Features
Brand
AFIXOSTAT
Full Details
Dosage Strength
40mg
Drug Ingredients
- Febuxostat
Drug Packaging
Film-Coated Tablet 1's
Generic Name
Febuxostat
Dosage Form
Film-Coated Tablet
Registration Number
DRP-12601
Drug Classification
Prescription Drug (RX)