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DB-10 Medroxyprogesterone Acetate 10mg Tablet 1's

RXDRUG-DRP-4426-1pc
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Description

Indications/Uses

For the treatment of menorrhagia and secondary amenorrhoea and mild to moderate endometriosis. And may also be used in the palliative treatment of some hormone-dependent malignant neoplasms.

Dosage/Direction for Use

The usual dose of medroxyprogesterone tablets is 5mg/10 mg daily. Secondary amenorrhoea is treated for 5 to 10 days. Uterine bleeding is treated for 5 to 10 days beginning on day 16 or 21 of the menstrual cycle. Endometrial hyperplasia is treated for 12 to 14 consecutive days beginning on the day 1 or 16 of the menstrual cycle.

Administration

May be taken with or without food.

Contraindications

Use with caution in: Decreased kidney function; epilepsy; asthma; women who suffer from migraines; heart blood pressure; women with a history or risk of blood vessels (thromboembolism, eg deep vein thrombosis or pulmonary embolism); diabetes; women with a history of depression.
Not to be used in: Decreased liver function; liver disease; severe disease of the arteries, eg that has caused angina or a heart attack; cancer of the breast or reproductive organs; abnormal vaginal bleeding of unknown cause; pregnancy; rare heredity blood disorder called porphyrias.
This medicine should not be used if patient is allergic to one or any of its ingredients. Please inform the doctor or pharmacist if the patient has previously experienced such allergy. If the patient has experienced an allergic reaction, stop using the medicine and inform the doctor or pharmacist immediately.

Special Precautions

Before the patient takes this medication, tell the doctor the patient's medical history (and family history), including: high blood pressure, seizures, migraine headaches, diabetes, asthma, heart disease or blood vessel problems, (e.g., stroke, heart attack), liver or kidney disease, blood clots, history of cancer, high blood level of cholesterol or fats, depression, excessive weight gain or fluids retention during menstrual cycle, jaundice (yellowing of skin or eyes). Because this drug can interfere with laboratory test, tell the doctors and laboratory personnel that the patients takes medroxyprogesterone. Due to the risk of fetal harm, this medication must not be used during pregnancy (especially during the first four months of pregnancy). If the patient become pregnant or possibly be pregnant, inform the doctor immediately. This drug passes into breast milk. Though there have been no reports (to date) of problems in nursing infants, breast-feeding while using very high doses of this medication is not recommended. Consult a doctor before breast-feeding.

Use In Pregnancy & Lactation

Pregnancy: Medroxyprogesterone inhibits fertility at high doses. It should not be given during pregnancy.
Nursing mothers: Medroxyprogesterone is secreted in breast milk. The effect on the infants has not been determined.

Adverse Reactions

Breast tenderness & leakage of liqd from the nipple; hives, acne, hair growth & hair loss; break-through bleeding, vag spotting of blood, changes in menstrual flow, increased/decreased wt, nausea, fever, insomnia, & jaundice; difficulty controlling blood glucose in diabetic patients. Increased risk of heart attacks, stroke, breast cancer, blood clots, & pulmonary emboli in postmenopausal women.

Drug Interactions

Amniglutehimide (Cytadren) may increase the elimination of medroxyprogesterone by the liver leading to a decreased in the concentration of medroxyprogesterone in blood and possibly a reduction in effectiveness of the medroxyprogesterone.

Storage

Store at temperatures not exceeding 30°C.

MedsGo Class

Oestrogens, Progesterones & Related Synthetic Drugs

Features

Brand
DB-10
Full Details
Dosage Strength
10 mg
Drug Ingredients
  • Medroxyprogesterone Acetate
Drug Packaging
Tablet 1's
Generic Name
Medroxyprogesterone Acetate
Dosage Form
Tablet
Registration Number
DRP-4426
Drug Classification
Prescription Drug (RX)
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