NOSTON Potassium Citrate 1.08g (10 mEq) Extended-Release Tablet 15's
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Features
- Potassium Citrate
Description
Indications/Uses
Dosage/Direction for Use
Treatment with Potassium Citrate should be added to a regimen that limits salt intake (avoidance of foods with high salt content and of added salt at the table) and encourages high fluid intake (urine volume should be at least two liters per day). The objective of treatment with Potassium Citrate is to provide potassium citrate in sufficient dosage to restore normal urinary citrate (greater than 320 mg/day and as close to the normal mean of 640 mg/day as possible), and to increase urinary pH to a level of 6.0 to 7.0.
Doses of Potassium Citrate greater than 100 mEq/day have not been studied and should be avoided.
Serum electrolytes (Sodium, Potassium, Chloride and Carbon Dioxide), serum creatinine, and complete blood count should be monitored every four months.
Treatment should be discontinued if there is hyperkalemia, a significant rise in serum creatinine, or a significant fall in blood hematocrit or hemoglobin.
Use in children: Safety and effectiveness in children has not been established.
Administration
Contraindications
Potassium Citrate is contraindicated in patients in whom there is cause for arrest or delay in tablet passage through the gastrointestinal tract, such as those suffering from delayed gastric emptying, esophageal compression, intestinal obstruction or stricture or those taking anticholinergic medication. Because of its ulcerogenic potential, Potassium Citrate should not be given to patients with peptic ulcer disease.
Potassium Citrate is contraindicated in patients with active urinary tract infection (with either urea splitting or other organisms, in association with either calcium or struvite stones).
Potassium Citrate is contraindicated in patients with renal insufficiency (glomerular filtration rate of less than 0.7 ml/kg/min), because of the danger of soft tissue calcification and increased risk for the development of hyperkalemia.
Special Precautions
Use In Pregnancy & Lactation
Use in lactation: The normal potassium ion content of human milk is about 13 mEq/l. It is not known if Potassium Citrate has an effect on this content. Caution should be exercised when Potassium Citrate is administered to a nursing woman.