Indications/Uses
For the treatment of gastrointestinal spasms, irritable colon and spastic constipation.
Dosage/Direction for Use
Adults: 1 to 2 tablets three to four times daily dose not exceeding 40 mg, or, as prescribed by a physician.
Contraindications
Hypersensitivity to dicycloverine or other ingredients in the product. Infants less than 6 months old; Patients with the following conditions: Myasthenia gravis, Obstructive uropathy, Obstructive disease of the GI tract, Paralytic ileus and intestinal atony, Severe ulcerative colitis.
Special Precautions
Should be used with caution in patients with glaucoma, prostatic hypertrophy, hiatal hernia associated with reflux esophagitis.
Adverse Reactions
Side effects of dicycloverine hydrochloride are dryness of the mouth, with difficulty in swallowing and talking, thirst, dilatation of the pupils (mydriasis) with loss of accommodation (cycloplegia) and photophobia, flushing and dryness of the skin, constipation and headache.
Toxic doses cause tachycardia, rapid respiration, hyperpyrexia and CNS stimulation marked by restlessness, confusion, excitement, paranoid and psychotic reactions, hallucinations and delirium and occasionally seizures and convulsion.
Treatment of Adverse Effects: If overdoses have been taken by mouth, the stomach should be emptied by aspiration and lavage or by induction of emesis. The giving of activated charcoal to reduce absorption prior to lavage has been suggested.
Toxic doses cause tachycardia, rapid respiration, hyperpyrexia and CNS stimulation marked by restlessness, confusion, excitement, paranoid and psychotic reactions, hallucinations and delirium and occasionally seizures and convulsion.
Treatment of Adverse Effects: If overdoses have been taken by mouth, the stomach should be emptied by aspiration and lavage or by induction of emesis. The giving of activated charcoal to reduce absorption prior to lavage has been suggested.
Storage
Store at temperatures not exceeding 30°C. Protect from light.
Action
Pharmacology: Dicycloverine hydrochloride is an antimuscarinic agent with effects similar to but much weaker than those of atropine. It also has a direct antispasmodic action on smooth muscles and reduces secretions, especially salivary and bronchial secretions. It also reduces perspiration, but has a little effect on biliary or pancreatic secretion. Dicycloverine hydrochloride is used in the gastrointestinal spasm, particularly that associated with the irritable bowel syndrome and is also given in association with antacids as adjunct in the treatment of peptic ulcer.
MedsGo Class
Antispasmodics
Features
Brand
RiteMed
Full Details
Dosage Strength
10mg
Drug Ingredients
- Dicycloverine
Drug Packaging
Tablet 1's
Generic Name
Dicycloverine Hydrochloride
Dosage Form
Tablet
Registration Number
DRP-2968-01
Drug Classification
Prescription Drug (RX)