RANITEIN Ranitidine 150mg - 1 Tablet

Indications / Uses

RANITEIN Ranitidine 150mg is used for the management and prevention of ulcers in the stomach and intestines, including those associated with non-steroidal anti-inflammatory drug (NSAID) use. It also provides symptomatic relief for conditions such as chronic episodic dyspepsia and gastroesophageal reflux disease (GERD). Furthermore, it is indicated for the treatment of erosive esophagitis, post-operative ulcers, and specialized hypersecretory conditions.

Formulation / Ingredients

RANITEIN Ranitidine 150mg contains: Ranitidine Hydrochloride 150mg

Side Effects

RANITEIN Ranitidine 150mg common side effects include headache, which can sometimes be severe, and gastrointestinal issues such as constipation, diarrhea, nausea, vomiting, or abdominal pain. Less common side effects reported involve the central nervous system, including dizziness, insomnia, and confusion (predominantly in severely ill and elderly patients). Rare, but serious effects, can include blood count changes (like leukopenia or thrombocytopenia) and reversible liver changes (such as hepatitis or jaundice) which require immediate cessation. Other rare effects reported include hypersensitivity reactions, cardiovascular issues like tachycardia or bradycardia, and musculoskeletal pain.

Directions and Dosage

• Dosage for Adults (18+ years):
  • For active ulcers/GERD: 150 mg twice daily OR 300 mg once daily at bedtime. Treatment is typically 4 to 8 weeks.
  • For severe erosive esophagitis: 150 mg four times daily for up to 12 weeks.
  • For maintenance/prevention: 150 mg once daily at bedtime.
  • For specialized hypersecretory conditions: Initial dose is 150 mg three times daily, which may be adjusted up to a maximum of 6 g per day in severe cases.
• Dosage for Kids 1 month - 16 years (Ulcers): Oral dose is 2 to 4 mg/kg twice daily. Do not exceed 300 mg per day.
• Dosage for Kids 1 month - 16 years (GERD/Esophagitis): Oral dose is 5 to 10 mg/kg per day, typically divided into 2 doses. Do not exceed 300 mg per day.

Dose adjustment is required for individuals with severe renal impairment (creatinine clearance less than 50 ml/min), where the recommended adult dose is 150 mg once at night. The total duration of treatment depends on the condition being treated and is generally short-term unless a maintenance regimen is recommended.

Contraindications

Do not use this product if there is a known history of hypersensitivity to the substance it contains. It must also be avoided in individuals with a history of acute porphyria, as administration may precipitate an attack.

Special Precautions

• Before starting therapy, especially when a stomach ulcer is present, the possibility of a serious malignancy should be ruled out, as symptomatic relief might mask the presence of cancer.
• Use with caution in individuals with pre-existing kidney or liver impairment, as reduced function in these organs may lead to accumulation and higher concentration of the drug in the body.
• Prolonged consumption may potentially interfere with the absorption of essential nutrients, specifically leading to vitamin B12 deficiency.
• Usage in pediatric patients has been associated with an increased risk for developing acute gastroenteritis and community-acquired pneumonia.

Is it safe to take it with other medications?

The absorption of this product can be affected by certain other medications; for example, antacids may decrease its absorption. Since this product reduces stomach acidity, it can change how well other drugs are absorbed, specifically those needing stomach acid to be properly absorbed (e.g., certain antifungals, atazanavir). Use with caution with drugs like warfarin as it may increase the risk of bleeding.

How should I store it?

The tablets should be stored at temperatures not exceeding 30ºC. Keep the product in its original packaging to protect it from moisture and light.

Used For

Anti-ulcer, GERD, Dyspepsia

Age

1 month & up