Indications/Uses
Treatment of duodenal and gastric ulcer. Also used for Helicobacter pylori eradication in peptic ulcer disease, reflux esophagitis and Zollinger-Ellison syndrome. Patients considered to be at risk of aspiration of gastric contents during general anesthesia/acid aspiration prophylaxis.
Dosage/Direction for Use
Reflux Esophagitis: Usual Dose: 20-40 mg once daily.
Maintenace Dose: Therapy can be continued with 20 mg once daily.
Zollinger-Ellison Syndrome: Initial Recommended Dose: 60 mg once daily, but doses of 20-120 mg daily may be used.
Maintenace Dose: Therapy can be continued with 20 mg once daily.
Zollinger-Ellison Syndrome: Initial Recommended Dose: 60 mg once daily, but doses of 20-120 mg daily may be used.
Administration
Should be taken with food: Take immediately before a meal.
Special Precautions
Before giving omeprazole to patients with gastric ulcers, the possibility of malignancy should be excluded since omeprazole may mask symptoms and delay diagnosis.
Adverse Reactions
Omeprazole are generally well tolerated. The adverse effects reported frequently with omeprazole have been diarrhea, constipation, skin rashes, nausea and headache.
Drug Interactions
Omeprazole interferes in the oxidation of warfarin, phenytoin, diazepam and cyclosporine.
Storage
Store at temperatures not exceeding 30°C.
Action
Pharmacokinetics: Omeprazole are enteric-coated to protect them from premature activation by gastric acid. After absorption in the duodenum, they are transported to the acid parietal cell canaliculus, where they are converted to active species. Metabolites of these agents are excreted in urine and feces.
MedsGo Class
Antacids, Antireflux Agents & Antiulcerants
Features
Dosage Strength
20 mg
Drug Ingredients
- Omeprazole
Drug Packaging
Capsule 1's
Generic Name
Omeprazole
Registration Number
DR-XY32461
Drug Classification
Prescription Drug (RX)
Product Questions
Questions
