XIGDUO XR Dapagliflozin / Metformin 10mg / 500mg - 1 Tablet

Indications / Uses

Xigduo XR 10mg / 500mg Tablet is used for managing type 2 diabetes mellitus in adults to improve blood sugar control when diet and exercise alone are insufficient. It combines two antihyperglycemic agents to reduce glucose levels through complementary mechanisms of action. This medication is also indicated to lower cardiovascular risk in patients with established heart disease.

Formulation / Ingredients
Xigduo XR 10mg / 500mg Tablet contains: Dapagliflozin 10mg + Metformin Hydrochloride 500mg

Side Effects

Xigduo XR 10mg / 500mg Tablet common side effects include: urinary tract infections, genital yeast infections, diarrhea, nausea, vomiting, and abdominal discomfort. Hypoglycemia may occur when combined with insulin or sulfonylureas. Serious side effects include lactic acidosis symptoms (muscle pain, dizziness), ketoacidosis, and volume depletion.

Directions and Dosage

• Adults (18+ years): 1 tablet once daily with evening meal. Do not exceed recommended dosage.

Not recommended for children under 18. Maximum treatment duration: long-term under medical supervision. Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²).

Contraindications

Severe kidney impairment, metabolic acidosis, diabetic ketoacidosis, history of hypersensitivity to components, acute conditions with dehydration risk.

Use in Pregnancy and Lactation

Avoid during pregnancy due to potential fetal risks. Discontinue during breastfeeding.

Special Precautions

• Monitor kidney function before and during treatment
• Correct dehydration before initiation
• Maintain genital hygiene due to infection risk
• Watch for ketoacidosis symptoms (nausea, vomiting, abdominal pain)

Is it safe to take it with other medications?

May interact with diuretics, corticosteroids, or other antidiabetic drugs. Monitor blood glucose levels when combining therapies. Avoid alcohol due to lactic acidosis risk.

How should I store it?

Store below 30°C in original packaging. Protect from moisture. Keep out of reach of children.

Used For

Type 2 Diabetes

Age

Adults only