Indications / Uses
TRAJENTA DUO Linagliptin / Metformin 2.5mg / 500mg is used for improving blood sugar control in adults with type 2 diabetes mellitus, utilized as an adjunct to diet and exercise. It is suitable for patients whose condition is not adequately managed by metformin alone or for those already controlled on the individual components. The medication can also be added to regimens including a sulfonylurea, SGLT2 inhibitor, or insulin when current therapy is insufficient.
Formulation / Ingredients
TRAJENTA DUO Linagliptin / Metformin 2.5mg / 500mg contains: Linagliptin 2.5mg + Metformin Hydrochloride 500mg
Do I need prescription to buy TRAJENTA DUO Linagliptin / Metformin 2.5mg / 500mg?
Yes, you need a prescription. But if you don't have one, you can get a free teleconsultation from MedsGo Physician. Just make an order and our Physician will call you back.
Side Effects
TRAJENTA DUO Linagliptin / Metformin 2.5mg / 500mg common side effects include: headache, nausea, change in taste, dizziness, and gastrointestinal issues like diarrhea and vomiting. Serious but less frequent effects include inflammation of the pancreas, severe and disabling joint pain, and the possibility of low blood sugar, especially when combined with other similar medications. There is also a rare but critical risk of a dangerous build-up of lactic acid in the blood.
Directions and Dosage
- Dosage for Adults (18+ years): This medication is typically administered twice daily with meals.
- The maximum total daily intake is 5 mg of the first component (linagliptin) and 2000 mg of the second component (metformin).
Not recommended for use in children below 18 years of age due to lack of established safety and efficacy data. Maximum treatment duration is not specified but is typically long-term.
Contraindications
The drug is not suitable for individuals with severe impairment of kidney function or kidney failure. It should not be used by those with acute or chronic metabolic acidosis, including a severe complication of diabetes. It is also contraindicated for individuals with significant liver disease or a known severe reaction to the components.
Use in Pregnancy and Lactation
The medication is considered unsafe for use during pregnancy, as evidence indicates a clear risk to the developing baby. It is also considered unsafe while breastfeeding, as data suggests the components may lead to toxicity in the infant.
Special Precautions
- Monitor kidney function regularly before and during administration.
- Potential for acute inflammation of the pancreas should be considered, especially if there is a history of the condition.
- Discontinuation is required before or during certain imaging procedures involving iodinated contrast dye.
- Caution is advised if the individual is experiencing stressful conditions like trauma, major surgery, or fever.
- There is a possibility of developing severe and disabling joint discomfort.
- Observe for signs of skin abnormalities such as lesions or blisters.
- May cause low levels of Vitamin B12.
Is it safe to take it with other medications?
A reduction in the dose of insulin or sulfonylurea-class medications may be necessary when used together, as the risk of low blood sugar is increased. Use with certain antibiotics, such as Rifampicin, may decrease the effectiveness of the drug. Alcohol should be avoided as it increases the risk of lactic acid accumulation.
How should I store it?
Keep the tablets in the original packaging until use. Store the product in a cool, dry place where the temperature stays below 30°C.
Used For
- Type 2 Diabetes
Age
- Adults (18+ years)
Features
- Linagliptin
- Metformin
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