Indications / Uses of Compounded SEMAGLUTIDE 40MG + Vit.B12 - Solution For Injection
Semaglutide is a prescription medication approved by the FDA for two main uses:
- Type 2 diabetes: Semaglutide helps manage blood sugar levels in adults with type 2 diabetes, along with diet and exercise . It works by increasing insulin production, reducing sugar production in the liver, and slowing down the absorption of sugar in the gut.
- Heart disease in certain high-risk patients: Semaglutide can also help reduce the risk of major cardiovascular events (such as heart attack, stroke, or cardiovascular death) in adults with type 2 diabetes who already have established heart disease.
What are the side-effects of Compounded SEMAGLUTIDE 40MG + Vit.B12 - Solution For Injection?
Possible Side Effects: Common side effects include nausea, vomiting, diarrhea, abdominal pain, decreased appetite, and constipation.
Warnings:
- Thyroid Tumors: Report symptoms of thyroid tumors.
- Pancreatitis, Renal Failure: Report pancreatitis or renal failure symptoms; Maintain adequate hydration.
- Vision Changes: Report any vision changes.
- Gallbladder Disease: Report symptoms of gallbladder disease.
- Hypoglycemia: Monitor for symptoms of hypoglycemia and report any difficulties with glycemic control.
- Mental Health Changes: Report worsening depression, suicidal ideation, or unusual changes in behavior.
Cardiac Symptoms: Report any increase in heart rate or heart palpitations while resting.
Dosage / Direction for Use of Compounded SEMAGLUTIDE 40MG + Vit.B12 - Solution For Injection
Instructions: Administer as directed by your healthcare provider. The medication is typically given as a subcutaneous injection in the abdomen, thigh, or upper arm. Rotate injection sites with each dose to avoid irritation.
Dosing: Dosing should be directed by your doctor. The standard dosing is provided below:
- 0.25mg (0.0625mL) each week for weeks 1 to 4
- 0.5mg (0.125mL) each week for weeks 5 to 8
- 1mg (0.25mL) each week for weeks 9 to 12
- 1.5mg (0.375mL) each week for weeks 13 to 16
- 2mg (0.5mL) each week for weeks 17 and onward
EXPECTED RESULTS:
Effectiveness: Semaglutide mimics the hormone GLP-1, enhancing insulin secretion, reducing appetite, and slowing gastric emptying, leading to better glucose control and weight loss.
Onset: Improvements in blood sugar control may be observed within a few days, with weight loss effects noticeable within weeks to months of consistent use.
Clinical Evidence: Clinical trials have shown Semaglutide to significantly reduce HbA1c levels and promote weight loss in adults, supporting its use in diabetes and weight management.
Contraindications
Hypersensitivity to the active substance or to any of the excipients listed in Description.
Special Precautions
Not for everyone:
- Type 1 diabetes: Semaglutide isn't suitable for managing Type 1 diabetes.
- Diabetic ketoacidosis: Don't use Semaglutide to treat diabetic ketoacidosis. It's not a substitute for insulin.
- Severe heart failure: Semaglutide safety in patients with severe heart failure (NYHA class IV) is unknown. It's best to avoid it in these cases.
Be aware of these potential side effects:
- Dehydration: Semaglutide may cause nausea, vomiting, and diarrhea, leading to dehydration. This can worsen kidney problems. Stay hydrated!
- Pancreatitis: Be aware of symptoms like severe stomach pain and vomiting. Stop Semaglutide and see your doctor immediately if you suspect pancreatitis.
Taking Semaglutide with other medications:
- Increased low blood sugar risk: Semaglutide can increase your risk of low blood sugar, especially with insulin or sulfonylurea medications. Monitor blood sugar closely and adjust medication doses with your doctor.
- Diabetic retinopathy: If you have diabetic retinopathy and take insulin with Semaglutide, your condition may worsen. Discuss the risks and benefits with your doctor and be closely monitored.
Other important information:
- Driving and machinery: Semaglutide typically doesn't affect driving or operating machinery.
- Sodium-free: Good news for those watching sodium intake!
- Track your medication: Keep a record of the Semaglutide batch number for better traceability.
- Caution while driving: If you take Semaglutide with medications that cause low blood sugar, be extra cautious while driving to avoid accidents.
Is it safe to take SEMAGLUTIDE 40MG + Vit.B12 - Solution For Injection with other drugs?
Semaglutide can slow down the emptying of your stomach, which may impact how quickly other medications you take by mouth get absorbed into your body.
Here's a breakdown of how Semaglutide interacts with some common medications:
Paracetamol: Semaglutide may slightly delay the absorption of paracetamol, but the overall amount absorbed remains the same. No dosage adjustment is needed for paracetamol when taken with Semaglutide.
Birth control pills: Semaglutide shouldn't affect the effectiveness of your birth control pills. Studies haven't shown any significant changes in hormone levels when taking both medications together.
Atorvastatin (cholesterol medication): Semaglutide may slightly delay the absorption of atorvastatin, but the overall amount absorbed remains sufficient.
Digoxin (heart medication): Semaglutide doesn't affect the absorption or peak levels of digoxin in your body.
Metformin (diabetes medication): Semaglutide doesn't affect the absorption or peak levels of metformin in your body.
Warfarin (blood thinner): Semaglutide doesn't directly affect warfarin, but it's recommended to monitor your blood clotting levels (INR) more frequently when starting Semaglutide while taking warfarin or similar blood thinners.
How should I store SEMAGLUTIDE 40MG + Vit.B12 - Solution For Injection?
Conditions:
- The solution must be transported using cold-shipping methods and stored in a refrigerator at a temperature between 2°C and 8°C (36°F to 46°F). Freezing the solution is not recommended.
Expiry and Beyond Use Dates:
- Beyond-Use Date: Semaglutide Subcutaneous Injection Solution should only be used 90 days from compounding.