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Indication
Depression & associated conditions of anxiety, bulimia nervosa, obsessive-compulsive & premenstrual dysphoric disorder.
Dosage
Initially, 20 mg once daily given as a single or in divided doses. Dose may be adjusted if necessary, within 3-4 weeks of initiation according to response. Max: 60 mg daily.
Administration
May be taken with or without food.
Contraindications
Unstable seizure disorders/epilepsy. Severe renal (GFR <10 mL/min) impairment. Concomitant use or within 2 weeks of discontinuing MAOIs (e.g. iproniazid) or within 5 weeks of discontinuing fluoxetine. Concurrent use with metoprolol, linezolid, IV methylene blue, pimozide, and thioridazine.
Special Precautions
Patient with history of suicide-related events or pre-existing suicidal ideation; bipolar disorder, history of mania or hypomania; history of seizure disorder or conditions predisposing to seizures (e.g. brain damage, alcoholism), diabetes mellitus, history of bleeding disorders, CV disease (e.g. history of MI, unstable heart disease), risk factors for QT prolongation (e.g. congenital long QT syndrome, history of prolonged QT) or conditions predisposing to arrhythmias (e.g. hypokalaemia, hypomagnesaemia, bradycardia, acute MI, uncompensated heart failure); volume depletion, raised intraocular pressure or at risk of acute narrow-angle glaucoma. Patient where weight loss is undesirable. CYP2D6 poor metabolisers. Concomitant electroconvulsive therapy. Delayed-release cap: Bariatric surgery (refer to specific institutional protocols). Avoid abrupt withdrawal. Hepatic and mild to moderate renal impairment. Children and elderly. Pregnancy and lactation.
Storage
Store between 15-30°C. Protect from light, heat and moisture.
MedsGo Class
Antidepressants
Features
Brand
Fluoxedin
Full Details
Dosage Strength
20 mg
Drug Ingredients
- Fluoxetine
Drug Packaging
Capsule 30's
Generic Name
Fluoxetine Hcl
Dosage Form
Capsule
Registration Number
DRP-8184
Drug Classification
Prescription Drug (RX)