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RITEMED Losartan Potassium 50mg Film-Coated Tablet 60's

RXDRUG-DRP-2183-02-60
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Description

Indications/Uses

Monotherapy or in combination w/ other antihypertensive agents for the treatment of HTN.
 

Dosage/Direction for Use

HTN Adult Initial & maintenance dose: 50 mg once daily, may be increased to 100 mg once daily. Patient w/ intravascular vol-depletion eg, those treated w/ high-dose diuretics, history of liver disease & moderate to severe renal disease 25 mg once daily. Total daily dose: 25-100 mg once or bid. Childn ≥6 yr Recommended starting dose: 0.7 mg/kg once daily up to a total of 50 mg, ≥50 kg 50 mg up to a max of 100 mg daily, ≥20-<50 kg 25 mg up to a max of 50 mg daily. Hypertensive patients w/ left ventricular hypertrophy Initially 50 mg once daily, add hydrochlorothiazide (HCTZ) 12.5 mg daily &/or increase losartan to 100 mg once daily followed by an increase in HCTZ 25 mg once daily based on BP response.
 

Administration

May be taken with or without food.
 

Contraindications

Pregnancy.
 

Special Precautions

Correct intravascular vol-depletion eg, those treated w/ high-dose diuretics prior to therapy. Monitor serum K levels in diabetic patients w/ nephropathy. Electrolyte/fluid imbalance. Reversible changes in renal function, severe CHF, uni- or bilateral renal artery stenosis; history of liver impairment. Concurrent use w/ K-sparing diuretics, K supplements or salt substitutes containing K & drugs affecting renin-angiotensin-aldosterone system. Ischemic cardiopathy or cerebrovascular disease. Lactation. Neonates, childn w/ GFR <30 mL/min/1.73 m2 & liver impairment. Infants w/ history of in utero exposure to losartan.
 

Adverse Reactions

CV, endocrine, GI, hematologic, liver/biliary; metabolic, musculoskeletal, nervous system/psychiatric, resp, skin, special senses & urogenital adverse effects. Asthenia, chest pain, edema, facial edema, fatigue, fever, infection, flu-like disease, orthostatic effects, syncope, trauma.
 

Drug Interactions

Lithium; K-sparing diuretics (eg, spironolactone, triamterene, amiloride), K supplements or K-containing salt substitutes; NSAIDs including selective COX-2 inhibitors; rifampicin; fluconazole.
 

MedsGo Class

Angiotensin II Antagonists

Features

Brand
RiteMed
Full Details
Dosage Strength
50mg
Drug Ingredients
  • Losartan
Drug Packaging
Film-Coated Tablet 60's
Generic Name
Losartan Potassium
Dosage Form
Film-Coated Tablet
Registration Number
DRP-2183-02
Drug Classification
Prescription Drug (RX)
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