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IRBE Irbesartan 150mg Film-Coated Tablet 100's

RXDRUG-DRP-5977
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Description

What is this medicine used for?

Irbesartan is a medicine widely used to treat high blood pressure. Irbesartan helps to prevent future strokes, heart attacks and kidney problems. This medicine is only available on prescription.

How much and how often should you use this medicine?

DOSAGE AND ADMINISTRATION

Hypertension

150 mg to 300 mg once daily.

The usual recommended initial and maintenance dose is 150 mg once daily.

In hypertensive type 2 diabetic patients: 150 mg-300 mg once daily.

Or, as prescribed by the physician.

Contraindications

Known hypersensitivity to the active substance or to any of the excipients.

Warning and Precautions

Precautions:

The drug can cause serious fetal harm (possibly death) if used during the last six months of pregnancy.

So when pregnancy is diagnosed, treatment with Irbesartan should be stopped immediately and if appropriate, alternative therapy should be started.

When Irbesartan is used in patients with impaired renal function, a periodic monitoring of potassium and creatinine serum levels is recommended. There is no experience regarding the administration of irbesartan in patients with a recent kidney transplantation.

The combination of lithium and irbesartan is not recommended.

PREGNANCY

Because of the possibility that irbesartan may have a harmful effect on the fetus, it should not be used during pregnancy.

Warnings:

Hypotension-Volume-Depleted Patients: Irbesartan has been rarely associated with hypotension in hypertensive patients without other co-morbid conditions. Symptomatic hypotension, as with ACE inhibitors, may be expected to occur in sodium/volume depleted patients such as those treated vigorously with diuretics and/or salt restriction, or on haemodialysis. Volume and/or sodium depletion should be corrected before initiating therapy with irbesartan or a lower starting dose should be considered.

Fetal/Neonatal Morbidity and Mortality : Although there is no experience with Irbesartan in pregnant women, in utero exposure to ACE.

Inhibitors given to pregnant women during the second and third trimesters has been reported to cause injury and death to the developing fetus. Thus, as for any drug that also acts directly on the renin- angiotensin-aldosterone system, irbesartan should not be used during pregnancy. If pregnancy is detected during therapy, Irbesartan should be discontinued as soon as possible.

General: As a consequence of inhibiting the renin-angiotensin-aldosterone system, changes in renal function may be anticipated in susceptible individuals. In patients whose renal function depends on the activity of the renin-angiotensin-aldosterone system (e.g., hypertensive patients with renal artery stenosis in one or both kidneys, or patients with severe congestive heart failure), treatment with drugs that affect this system has been associated with oliguria and/or progressive azotemia and (rarely) with acute renal failure and/or death. The possibility of a similar effect occurring with the use of an angiotensin II receptor antagonist, including Irbesartan cannot be excluded.

In hypertensive type 2 diabetic patients with proteinuria (>900 mg/day), a population which has a high risk or renal artery stenosis, no patient treated with Irbesartan in IDNT had an early acute rise in serum creatinine attributable to renal artery stenosis.

Features

Brand
Irbe
Full Details
Dosage Strength
150mg
Drug Ingredients
  • Irbesartan
Drug Packaging
Film-Coated Tablet 100's
Generic Name
Irbesartan
Dosage Form
Film-Coated Tablet
Registration Number
DRP-5977
Drug Classification
Prescription Drug (RX)
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