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Indications/Uses
Prophylaxis for thromboembolic events. Acute coronary syndromes including unstable angina & non-Q wave MI.
Dosage/Direction for Use
Acute coronary syndrome Loading dose: 300 mg followed by 75 mg daily. Prophylaxis of thromboembolic events 75 mg once daily. Management of acute coronary syndromes, unstable angina & non-Q wave MI Loading dose: 300 mg followed by 75 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Active pathological bleeding eg, peptic ulcer or intracranial hemorrhage.
Special Precautions
Thrombotic thrombocytopenic purpura may occur after a short exposure (<2 wk). Patients w/ hematopoietic disorders eg, neutropenia or thrombocytopenia, hemorrhagic diathesis or other hemorrhagic disorders associated by a prolonged bleeding time or conditions w/ an increased risk of bleeding eg, GI ulcers, acute cerebral hemorrhage or severe liver dysfunction. Perform full blood counts prior to treatment & every 2 wk during 1st 3 mth of therapy & w/in 2 wk after treatment. Discontinue therapy 10-14 days before elective surgery.
Adverse Reactions
GI disturbances, skin rashes, blood dyscrasias including neutropenia & thrombocytopenia purpura, hemorrhagic disorders, hepatitis & cholestatic jaundice.
Drug Interactions
May potentiate effect of aspirin on collagen-induced platelet aggregation. Risk of increased occult GI blood loss w/ NSAIDs. May interfere the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, torsemide & fluvastatin.
MedsGo Class
Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)
Features
Brand
Platz
Full Details
Dosage Strength
75mg
Drug Ingredients
- Clopidogrel
Drug Packaging
Film-Coated Tablet 1's
Generic Name
Clopidogrel Bisulfate
Dosage Form
Film-Coated Tablet
Registration Number
DRP-4698-01
Drug Classification
Prescription Drug (RX)