NEBIL Nebivolol 2.5mg - 1 Tablet

Indications / Uses

NEBIL Nebivolol 2.5mg is used for the management of essential hypertension, working to lower high blood pressure often in combination with other anti-hypertensive agents. It is also indicated as an essential addition to standard therapeutic regimens for treating stable mild and moderate chronic heart failure. This is particularly relevant for elderly patients aged 70 years and older. As a beta-blocker, the medicine works by slowing the heart rate and reducing the force of heart contractions, which ultimately helps reduce the burden on the cardiovascular system.

Formulation / Ingredients
NEBIL Nebivolol 2.5mg contains: Nebivolol Hydrochloride 2.5mg

Side Effects

NEBIL Nebivolol 2.5mg common side effects include headache, dizziness, and feelings of general fatigue or weakness. Gastrointestinal disturbances such as nausea and diarrhea are also frequently reported effects. Other notable reactions can include the appearance of swelling, especially in the lower limbs, or sleep disturbances like vivid dreams. Serious, though less common, effects can involve significant breathing difficulty or signs of acute heart problems, which must be addressed immediately.

Directions and Dosage

• Dosage for Adults (Hypertension): The standard starting dose is 5 mg once daily; however, the 2.5 mg strength may be used to initiate therapy in some individuals.
• Dosage adjustments should be made gradually, with a maximum daily dose not to exceed 40 mg for hypertension.
• Dosage for Elderly (≥70 years, Heart Failure): The initial dose for heart failure treatment is 1.25 mg once daily, increased slowly. The 2.5 mg tablet is used during the titration phase.
• Dosage for Patients with Kidney or Liver Impairment: The recommended initial dose is 2.5 mg once daily, increased only if necessary.

Safety and efficacy have not been established in patients under 18 years of age. Treatment must not be stopped suddenly.

Contraindications

This medicine is restricted for use in patients with known allergy to the formulation components. It must not be taken by individuals who have a dangerously slow heart rate, severe heart conduction disturbances, or certain serious heart conditions like cardiogenic shock or acute heart failure. It is also restricted in cases of severe liver impairment, severe asthma, and metabolic disorders such as metabolic acidosis.

Use in Pregnancy and Lactation

The use of this treatment during gestation should be weighed against the risks, as animal studies have indicated potential effects on the fetus. It is not known if the substance passes into human milk; however, because of the possibility of serious adverse reactions in infants, use while nursing is not recommended.

Special Precautions

• Exercise caution when administered to individuals with kidney disease, moderate liver impairment, or circulation problems in the limbs.
• Sudden cessation of treatment must be avoided, as this may lead to worsening chest pain, irregular heartbeat, or acute cardiovascular events.
• It should be used carefully in patients with diabetes or an overactive thyroid, as the substance may mask symptoms like a rapid heart rate.

Is it safe to take it with other medications?

The combined use of this medication with other heart rate-slowing agents, such as certain calcium-channel blockers, can lead to an additive effect, potentially requiring close monitoring. Combining it with certain drugs for depression or irregular heart rhythm can increase its levels in the body, raising the risk of side effects.

How should I store it?

Store the tablets at temperatures not exceeding 30°C. Keep them protected from light and moisture, and ensure they remain securely out of reach of children.

Used For

High Blood Pressure, Heart Failure

Age

Adults