MELOZAR 125 Losartan / Hydrochlorothiazide 100mg / 25mg - 1 Tablet

Indications / Uses

MELOZAR 125 Losartan / Hydrochlorothiazide 100 / 25 is used for the treatment of high blood pressure (hypertension) in patients for whom combination therapy is considered appropriate. This fixed-dose combination is also used to reduce the risk of stroke in patients who have high blood pressure and left ventricular hypertrophy (enlargement of the heart muscle).

Formulation / Ingredients

MELOZAR 125 Losartan / Hydrochlorothiazide 100 / 25 contains: Losartan potassium 100 mg + Hydrochlorothiazide 25 mg

Side Effects

MELOZAR 125 Losartan / Hydrochlorothiazide 100 / 25 common side effects include upper respiratory infection, dizziness, and back pain. Other possible effects may involve feeling tired, headache, or a dry cough. Infrequently observed effects can include digestive system discomfort like diarrhea or nausea. If you experience severe symptoms like persistent dizziness, irregular heartbeats, or signs of an allergic reaction (e.g., swelling), seek immediate attention.

Directions and Dosage

• Dosage for Adults: The usual initial and maintenance dose is one tablet of the lower strength (Losartan 50 mg + HCTZ 12.5 mg) once daily.
• Maximum Adult Dosage: If the response is inadequate, the dose may be increased to a maximum of one tablet of the higher strength (Losartan 100 mg + HCTZ 25 mg) once daily.

Not recommended for children and adolescents under 18 years old due to lack of experience.

Contraindications

• Hypersensitivity to the active substances or any component of the product.
• Known allergy to sulfonamide-derived drugs (due to the presence of one of the ingredients).
• Inability to produce urine (anuria).
• Severe impairment of liver or kidney function.
• Low potassium or high calcium levels that do not respond to treatment.
• Symptomatic high uric acid levels or history of gout.

Special Precautions

• Monitor for low blood pressure, especially in those with volume or salt depletion (e.g., those on high-dose water pills). Correct depletion before starting treatment.
• Use with caution in patients with fluid or electrolyte imbalance, diabetes, or a history of allergy or bronchial asthma.
• Watch for signs of liver or kidney problems; the combination product is not recommended for severe kidney impairment.
• May cause temporary near-sightedness and a form of glaucoma. Stop use immediately if vision changes or eye pain occurs.

Is it safe to take it with other medications?

Caution is advised when taken alongside certain other medications, including those for blood pressure, anti-inflammatory drugs, or potassium-sparing diuretics. This can lead to undesirable effects such as low blood pressure or changes in blood electrolyte levels. Specific monitoring may be required if taken with certain drugs for mood or cholesterol.

How should I store it?

Store at temperatures not exceeding 30°C. Keep it protected from light and moisture.

Used For

Hypertension, Stroke Risk Reduction

Age

Adults 18+ years