FELOSTAL-5 ER Felodipine 5mg Extended-Release Tablet 1's
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CODE | Dosage Strength | Drug Packaging | Availability | Price | ||
---|---|---|---|---|---|---|
RXDRUG-DRP-2983-1pc
|
In stock
|
₱900 |
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Features
- Felodipine
Description
Indications/Uses
Dosage/Direction for Use
Overdosage
Administration
Contraindications
Warnings
Special Precautions
Use In Pregnancy & Lactation
Adverse Reactions
Drug Interactions
Storage
Action
It has been shown by electro-physiological studies that Felodipine has no direct effect on conduction in the specialized conducting system of the heart and has no effect on the AV nodal refractoriness.
Felodipine produces an increase in heart rate which is counteracted when concurrent beta receptor blockers are administered.
Pharmacokinetics: Felodipine is almost completely absorbed from the gastrointestinal tract after oral doses but undergoes extensive first-pass metabolism, with a bioavailability of about 15% (range 10 to 25%). It is extensively metabolized in the gut and the liver and is excreted almost entirely as metabolites, about 70% of a dose being excreted in urine and the remainder in feces. The terminal elimination half-life is reported to be about 11 to 16 hours after oral administration of an immediate-release preparation, but longer with a modified release formulation. Felodipine is about 99% bound to plasma proteins.