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Indications/Uses
Treatment of candidiasis in the oral cavity.
Dosage/Direction for Use
Intestinal or Esophageal Candidiasis: Adults: 500,000 iu (5 mL) or 1,000,000 iu (10 mL) 3 or 4 times a day.
Children: ≥100,000 iu (1 mL) may be given 4 times daily.
Lesions of the Mouth: 100,000 iu (1 mL) 4 times daily.
Infants Born to Mothers with Vaginal Candidiasis: 100,000 iu (1 mL) daily.
The preparation should be retained in the mouth as long as possible before swallowing and patients should avoid taking food or drink earlier than 1 hr after a dose.
Children: ≥100,000 iu (1 mL) may be given 4 times daily.
Lesions of the Mouth: 100,000 iu (1 mL) 4 times daily.
Infants Born to Mothers with Vaginal Candidiasis: 100,000 iu (1 mL) daily.
The preparation should be retained in the mouth as long as possible before swallowing and patients should avoid taking food or drink earlier than 1 hr after a dose.
Administration
Should be taken on an empty stomach: Retain susp in the mouth for as long as possible before swallowing. Do not take food/drink at least 1 hr after a dose.
Adverse Reactions
Diarrhea, gastrointestinal distress, nausea and vomiting. Oral irritation and sensitization may occur. Rashes, including urticaria, and rarely Stevens-Johnson syndrome have been reported.
Storage
Store at a temperature not exceeding 25°C. Shake gently before using.
Action
Pharmacology: Nystatin acts by binding to sterols in the cell membrane of the fungus which interferes in the membrane permeability. It exhibits no appreciable activity against bacteria or trichomonads.
Following oral administration, nystatin is poorly absorbed with no detectable blood levels when given in the recommended doses. Most of the orally administered nystatin is passed unchanged in the stool.
Following oral administration, nystatin is poorly absorbed with no detectable blood levels when given in the recommended doses. Most of the orally administered nystatin is passed unchanged in the stool.
MedsGo Class
Antifungals
Features
Brand
Afunginal
Full Details
Dosage Strength
100.000 units / ml
Drug Ingredients
- Nystatin
Drug Packaging
Oral Suspension 30ml
Generic Name
Nystatin
Dosage Form
Oral Suspension
Registration Number
DRP-587
Drug Classification
Prescription Drug (RX)