Indications/Uses
Infections due to β-lactamase-producing strains (where amoxicillin alone is not appropriate) including resp tract, genitourinary & abdominal infections; cellulitis, animal bites, severe dental infection w/ spreading cellulitis.
Dosage/Direction for Use
Adult & childn >12 yr Mild to moderate infections 375 mg 8 hrly or 625 mg 12 hrly. Dental abscess 375 mg 8 hrly for 5 days. Severe infections including chronic & recurrent UTI & lower resp tract infections 625 mg 8 hrly or 1 g 12 hrly. Hemodialysis 375 or 625 mg 24 hrly. Renal impairment CrCl 10-30 mL/min 375 or 625 mg 12 hrly, CrCl <10 mL/min 375 mg 12 hrly.
Administration
May be taken with or without food: Best taken at the start of meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity to penicillins. Cross-sensitivity w/ other β-lactam antibiotics eg, cephalosporins. Previous history of jaundice/liver impairment associated w/ penicillins. Glandular fever or lymphatic lymphoma.
Special Precautions
Hepatic & renal impairment. Pregnancy & lactation.
Adverse Reactions
Hypersensitivity reactions & GI disturbances. Reversible leukopenia & thrombocytopenia, thrombocytopenic purpura, agranulocytosis, anemia, slight thrombocytosis, eosinophilia, abnormal platelet aggregation, prolonged bleeding & prothrombin time. Dizziness, headache, reversible hyperactivity & convulsions, agitation, anxiety, behavioral changes, confusion, insomnia. Increased AST & ALT, serum bilirubin & alkaline phosphatase; hepatitis, cholestatic jaundice, acute hepatic dysfunction. Acute interstitial nephritis, crystalluria, vag itching, soreness & discharge. Superficial tooth discoloration.
Drug Interactions
Probenecid, allopurinol, methotrexate, OCs, warfarin, disulfiram.
MedsGo Class
Penicillins
Features
Brand
RiteMed
Full Details
Dosage Strength
625mg
Drug Ingredients
- Co-Amoxiclav
Drug Packaging
Film-Coated Tablet 1's
Generic Name
Co-Amoxiclav
Dosage Form
Film-Coated Tablet
Registration Number
DRP-1291-05
Drug Classification
Prescription Drug (RX)
View all variations as list
| CODE | Dosage Strength | Drug Packaging | Availability | Price | ||
|---|---|---|---|---|---|---|
|
RXDRUG-DRP-1291-05-1pc
|
In stock
|
₱3650 |