Please sign in so that we can notify you about a reply
- All about product
- Features
- Product Questions
Indications/Uses
Respiratory Tract Infections: Tonsillitis, pharyngitis, pneumonia, bronchitis, bronchiectasis, lung abscesses, emphysema, pleuritis, sinusitis, laryngitis, otitis media.
Urinary Tract Infections: Pyelonephritis, cystitis, adnexitis, endometritis.
Skin and Soft Tissue Infections: Lymphangitis, abscesses, cellulitis, decubitus ulcers, mastitis, furunculosis, erysipelas.
Urinary Tract Infections: Pyelonephritis, cystitis, adnexitis, endometritis.
Skin and Soft Tissue Infections: Lymphangitis, abscesses, cellulitis, decubitus ulcers, mastitis, furunculosis, erysipelas.
Dosage/Direction for Use
Adults: Treatment of Uncomplicated Urinary Tract Infections eg, Cystitis: 1-2 g daily, given as single dose or in 2 equally divided doses.
Other Urinary Tract Infections: 2 g daily or in 2 equally divided doses.
Skin and Skin Structure Infections: 1 g daily given as a single dose or in 2 equally divided doses.
Treatment of Group A β-Hemolytic Streptococci, Pharyngitis and Tonsillitis: The usual dosage is 1 g daily, as a single dose or in 2 equally divided doses for at least 10 days.
Respiratory Infections: Usual dosage is 1 g/day in 2 divided doses (500 mg 2 times a day).
Moderate to Severe Infections: Recommended Dosage: 1-2 g daily in 2 divided doses (500-1000 mg every 12 hrs).
Children: Urinary Tract Infections and Skin Infections: 30 mg/kg/day in divided doses every 12 hrs.
Pharyngitis and Tonsillitis: 30 mg/kg of body weight/day in a single dose or in 2 divided doses.
Treatment of infection caused by group A β-hemolytic streptococcus is given for at least 10 days.
Administration: Syrup: Prepare suspension at time of dispensing by adding 37 mL of water. Shake well before use.
Other Urinary Tract Infections: 2 g daily or in 2 equally divided doses.
Skin and Skin Structure Infections: 1 g daily given as a single dose or in 2 equally divided doses.
Treatment of Group A β-Hemolytic Streptococci, Pharyngitis and Tonsillitis: The usual dosage is 1 g daily, as a single dose or in 2 equally divided doses for at least 10 days.
Respiratory Infections: Usual dosage is 1 g/day in 2 divided doses (500 mg 2 times a day).
Moderate to Severe Infections: Recommended Dosage: 1-2 g daily in 2 divided doses (500-1000 mg every 12 hrs).
Children: Urinary Tract Infections and Skin Infections: 30 mg/kg/day in divided doses every 12 hrs.
Pharyngitis and Tonsillitis: 30 mg/kg of body weight/day in a single dose or in 2 divided doses.
Treatment of infection caused by group A β-hemolytic streptococcus is given for at least 10 days.
Administration: Syrup: Prepare suspension at time of dispensing by adding 37 mL of water. Shake well before use.
Administration
May be taken with or without food: May be taken w/ meals to reduce GI discomfort.
Contraindications
Hypersensitivity to cephalosporins or to any of the components of Drozid.
Special Precautions
In penicillin-allergic patients due to the possibility of cross-allergy. If a hypersensitivity reaction occurs, cefadroxil should be discontinued and the patient treated with usual agents (eg, epinephrine or other pressor amines, antihistamines or corticosteroids).
Should be used with caution in the presence of impaired renal function (CrCl <50 mL/min/1.73 m2) and patients with colitis.
Reproduction study in mice and rats with doses up to 11 times the human dose have revealed no evidence of impaired fertility or harm to the fetus due to cefadroxil, there are however, no adequate and well-controlled studies in pregnant women.
Prolonged use of cefadroxil may result in the overgrowth of nonsusceptible organisms.
Positive Benedict's, Fehling's or Clinitest tablet's test in glycosuria were reported during treatment with cefadroxil. But not if using enzymatic reaction like Clinistix.
Use in pregnancy & lactation: Although there have been no reports of adverse effects to the fetus to date, safe use of cephalosporins during pregnancy has not been definitely established.
Cefadroxil should be used during pregnancy only when clearly needed.
Cephalosporins are distributed into milk, so cefadroxil should be used with caution in nursing women.
Should be used with caution in the presence of impaired renal function (CrCl <50 mL/min/1.73 m2) and patients with colitis.
Reproduction study in mice and rats with doses up to 11 times the human dose have revealed no evidence of impaired fertility or harm to the fetus due to cefadroxil, there are however, no adequate and well-controlled studies in pregnant women.
Prolonged use of cefadroxil may result in the overgrowth of nonsusceptible organisms.
Positive Benedict's, Fehling's or Clinitest tablet's test in glycosuria were reported during treatment with cefadroxil. But not if using enzymatic reaction like Clinistix.
Use in pregnancy & lactation: Although there have been no reports of adverse effects to the fetus to date, safe use of cephalosporins during pregnancy has not been definitely established.
Cefadroxil should be used during pregnancy only when clearly needed.
Cephalosporins are distributed into milk, so cefadroxil should be used with caution in nursing women.
Use In Pregnancy & Lactation
In penicillin-allergic patients due to the possibility of cross-allergy. If a hypersensitivity reaction occurs, cefadroxil should be discontinued and the patient treated with usual agents (eg, epinephrine or other pressor amines, antihistamines or corticosteroids).
Should be used with caution in the presence of impaired renal function (CrCl <50 mL/min/1.73 m2) and patients with colitis.
Reproduction study in mice and rats with doses up to 11 times the human dose have revealed no evidence of impaired fertility or harm to the fetus due to cefadroxil, there are however, no adequate and well-controlled studies in pregnant women.
Prolonged use of cefadroxil may result in the overgrowth of nonsusceptible organisms.
Positive Benedict's, Fehling's or Clinitest tablet's test in glycosuria were reported during treatment with cefadroxil. But not if using enzymatic reaction like Clinistix.
Use in pregnancy & lactation: Although there have been no reports of adverse effects to the fetus to date, safe use of cephalosporins during pregnancy has not been definitely established.
Cefadroxil should be used during pregnancy only when clearly needed.
Cephalosporins are distributed into milk, so cefadroxil should be used with caution in nursing women.
Should be used with caution in the presence of impaired renal function (CrCl <50 mL/min/1.73 m2) and patients with colitis.
Reproduction study in mice and rats with doses up to 11 times the human dose have revealed no evidence of impaired fertility or harm to the fetus due to cefadroxil, there are however, no adequate and well-controlled studies in pregnant women.
Prolonged use of cefadroxil may result in the overgrowth of nonsusceptible organisms.
Positive Benedict's, Fehling's or Clinitest tablet's test in glycosuria were reported during treatment with cefadroxil. But not if using enzymatic reaction like Clinistix.
Use in pregnancy & lactation: Although there have been no reports of adverse effects to the fetus to date, safe use of cephalosporins during pregnancy has not been definitely established.
Cefadroxil should be used during pregnancy only when clearly needed.
Cephalosporins are distributed into milk, so cefadroxil should be used with caution in nursing women.
Adverse Reactions
Nausea, vomiting & diarrhea. Rash, urticaria & angioedema. Pyrosis, anorexia, dyspepsia, abdominal pain, headache, dizziness, moniliasis, vaginitis & pseudomembranous colitis.
Drug Interactions
Concomitant administration of oral probenecid competitively inhibits tubular secretion resulting in higher and more prolonged serum concentration of most cephalosporins.
Concurrent use of nephrotoxic agents eg, aminoglycosides, colistin, polymyxin B or vancomycin may increase the risk of nephrotoxicity with some cephalosporins and probably should be avoided, if possible may be additive or synergistic with aminoglycoside or penicillins against some organisms.
Concurrent use of nephrotoxic agents eg, aminoglycosides, colistin, polymyxin B or vancomycin may increase the risk of nephrotoxicity with some cephalosporins and probably should be avoided, if possible may be additive or synergistic with aminoglycoside or penicillins against some organisms.
Storage
Store at room temperature not exceeding 30°C. Protect from light.
Action
Pharmacology: Cefadroxil is rapidly and almost completely absorbed from the gastrointestinal tract. The rate of absorption is unaffected by food. Peak serum concentration 16 and 28 mg/mL are attained within 1-2 hrs after a single 500-mg and 1000-mg oral dose, respectively. The serum t½ of cefadroxil is 1-2 hrs in adults with normal renal function and prolonged in patients with impaired renal function. Cefadroxil is excreted unchanged about 70-90% within 24 hrs. Renal elimination of cefadroxil is substantially reduced in patients with impaired renal function. In vitro test demonstrates that the cephalosporins are bactericidal because of their inhibition of cell wall synthesis.
Sensitive gram-positive organisms are: Penicillinase and staphylococcus which do not produce penicillinase; group A β-hemolytic streptococci, Streptococcus pneumoniae and Streptococcus pyogenes.
Sensitive gram-negative organisms are: E. coli, Klebsiella pneumoniae and some strains of P. mirabilis and Haemophilus influenzae.
Sensitive gram-positive organisms are: Penicillinase and staphylococcus which do not produce penicillinase; group A β-hemolytic streptococci, Streptococcus pneumoniae and Streptococcus pyogenes.
Sensitive gram-negative organisms are: E. coli, Klebsiella pneumoniae and some strains of P. mirabilis and Haemophilus influenzae.
MedsGo Class
Cephalosporins
Features
Dosage Strength
500 mg
Drug Ingredients
- Cefadroxil
Drug Packaging
Capsule 1's
Generic Name
Cefadroxil
Registration Number
DRP-8421
Drug Classification
Prescription Drug (RX)
Questions and Answers about DROZID Cefadroxil 500mg Capsule 1's
Questions
