CEFIMED-100 Cefepime 1g Powder for Injection - 1 Vial

Indications / Uses

CEFIMED-100 Cefepime 1g Vial is used for the treatment of various bacterial infections in different parts of the body, including moderate to severe pneumonia, uncomplicated and complicated urinary tract infections, and uncomplicated skin and skin structure infections. It is also indicated for complicated intra-abdominal infections, often in combination with another suitable agent, and for the empiric treatment of fever in individuals with a low white blood cell count (febrile neutropenia). This product belongs to a class of powerful anti-bacterial agents that work by destroying susceptible bacteria.

Formulation / Ingredients

CEFIMED-100 Cefepime 1g Vial contains: Cefepime (as Hydrochloride) 1g + Arginine USP

Side Effects

CEFIMED-100 Cefepime 1g Vial common side effects include adverse reactions at the injection site such as pain, inflammation, or redness, and gastrointestinal issues like diarrhea, nausea, or vomiting. More serious, though less frequent, adverse effects involve the nervous system and may present as confusion, muscle twitching, seizures, or an altered state of consciousness, especially if kidney function is reduced. It can also rarely lead to severe diarrhea, known as antibiotic-associated colitis, which may occur even weeks after stopping treatment.

Directions and Dosage

• Dosage for Adults (18+ years) for mild to moderate infections: 0.5 g to 1 g every 12 hours.
• Dosage for Adults (18+ years) for severe infections: 2 g every 12 hours.
• Dosage for Adults (18+ years) for severe neutropenic fever: 2 g every 8 hours.
• Dosage for Kids (over 2 months and up to 40 kg) for most infections: 50 mg per kg body-weight every 12 hours.
• Dosage for Kids (over 2 months and up to 40 kg) for febrile neutropenia: 50 mg per kg body-weight every 8 hours.

Doses should not exceed 2 g every 8 hours for any patient. The duration of treatment is typically 7 to 10 days, or until the fever resolves in neutropenic patients, but can be up to 21 days for certain severe infections.

Contraindications

This product is contraindicated if there is a known history of severe allergic reaction to the product itself, to other agents of the same class, or a previous severe immediate allergic reaction to penicillin-type anti-bacterial agents.

Use in Pregnancy and Lactation

Use during pregnancy and breastfeeding is only advised when the need for the product is clear.

Special Precautions

• Dosage adjustments are necessary in individuals with reduced kidney function to prevent drug accumulation and potential toxicity.
• Caution is necessary in individuals with a history of digestive tract disease, particularly colitis.
• Prolonged use may lead to a secondary infection with resistant organisms or fungi.
• Monitoring of kidney and blood status is necessary, especially during high-dose or extended treatment periods.

Is it safe to take it with other medications?

Co-administration with potent diuretics or other anti-bacterial agents of the aminoglycoside class can increase the risk of kidney-related side effects, so monitoring kidney function is important. The effectiveness of certain vaccines (e.g., typhoid) may be reduced when administered concurrently.

How should I store it?

The powder should be stored at temperatures not exceeding 30°C. Once prepared, the solution has a limited shelf life and must be used promptly or stored as directed.

Used For

Bacterial Infections

Age

2 months & up