BACTIV Co-Amoxiclav 500mg / 100mg Powder for IV Injection 10mL
RXDRUG-DRP-389
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FDA-registered Products
FDA-licensed Pharmacies
Features
Brand
Bactiv
Full Details
Dosage Strength
500 mg / 100 mg
Drug Ingredients
- Co-Amoxiclav
Drug Packaging
Powder for Injection (I.V.) 10ml
Generic Name
Co-Amoxiclav
Dosage Form
Powder For Injection (I.V.)
Registration Number
DRP-389
Drug Classification
Prescription Drug (RX)
Description
Indications/Uses
Treatment of infections caused by susceptible gm +ve & gm -ve microorganisms.
Dosage/Direction for Use
Tab Adult & childn ≥40 kg 625 mg 12 hrly or 375 mg 8 hrly. More severe & resp tract infections 1 g 12 hrly or 625 mg 8 hrly. Inj Adult & childn >12 yr 1.2 g 8 hrly. Serious infections 6 hrly. Childn 3 mth-12 yr 30 mg/kg 8 hrly. Serious infections 6 hrly. Childn 0-3 mth 30 mg/kg 12 hrly in premature infants & 8 hrly in full-term infants during perinatal period. Surgical prophylaxis 1.2 g IV at anesth induction. High-risk infection eg, colorectal surgery 3-4 doses of 1.2 g in 24-hr period (at 0, 8, 16 & 24 hr).
Administration
May be taken with or without food: Take at the start of a meal for better absorption & to minimize GI intolerance.
Contraindications
Penicillin hypersensitivity. Possible cross-sensitivity w/ other β-lactam antibiotics eg, cephalosporins. History of penicillin-associated jaundice/hepatic dysfunction.
Special Precautions
Hepatic dysfunction, moderate to severe renal impairment. Periodic assessment of hepatic, renal & hematopoietic function during prolonged therapy or in patients w/ severe hepatic impairment. Maintain adequate fluid intake & urinary output especially in high doses of amoxicillin. Avoid prolonged use. Prolonged bleeding & prothrombin time. Concomitant use w/ anticoagulants. Pregnancy & lactation.
Adverse Reactions
Diarrhea, pseudomembranous colitis, indigestion, vomiting, mucocutaneous candidiasis, nausea, hepatitis, cholestatic jaundice. Moderate & asymptomatic rise in AST, ALT or alkaline phosphatase; urticarial & erythematous skin rashes; transient leukopenia & thrombocytopenia. Inj: Local irritation, induration & phlebitis at inj site.
Drug Interactions
Decreased renal tubular secretion w/ probenecid. Disulfiram-like reaction w/ alcohol. Reduced efficacy of OCs.
MedsGo Class
Penicillins
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