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Indications/Uses
Used to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.
Dosage/Direction for Use
The usual initial dose is 16 mg three times daily taken preferably with meals; maintenance doses are generally in the range of 24 to 48 mg daily.
Administration to children is not recommended.
The dosage should be individually adapted according to response. Improvement can sometimes only be observed after a couple of weeks of treatment. The best results are sometimes obtained after a few months. These are indications for the treatment from the onset of the disease and/or the loss of hearing in the later phases of the disease.
Administration to children is not recommended.
The dosage should be individually adapted according to response. Improvement can sometimes only be observed after a couple of weeks of treatment. The best results are sometimes obtained after a few months. These are indications for the treatment from the onset of the disease and/or the loss of hearing in the later phases of the disease.
Administration
Should be taken with food.
Contraindications
Hypersensitivity to the active substance or any of the excipients.
Special Precautions
Not recommended in childn.
Adverse Reactions
Gastrointestinal disturbances, headache, skin rashes and pruritus.
Storage
Store at temperatures not exceeding 30°C.
Action
Pharmacology: The mechanism of action of Betahistine Hydrochloride is not known. Pharmacological testing in animals has shown that the blood circulation in the striae vascularis of the inner ear improved, probably by means of relaxation of the precapillary sphincter of the microcirculation of the inner ear. In pharmacological studies, Betahistine Hydrochloride was found to have weak H1-receptor agonism and considerable H3 antagonist properties in the CNS and autonomic nervous system. Betahistine Hydrochloride was found to have a dose-dependent inhibiting effect on spike generation of neurons in lateral and medial vestibular nuclei. The importance of this observation in the action against Meniere's syndrome of vestibular vertigo, however, remains unclear.
Betahistine Hydrochloride is completely absorbed after oral administration.
Only one metabolite, 2-pyridylacetic acid, which is excreted in the urine, is known.
Betahistine Hydrochloride is completely absorbed after oral administration.
Only one metabolite, 2-pyridylacetic acid, which is excreted in the urine, is known.
MedsGo Class
Features
Dosage
16 mg
Ingredients
- Betahistine
Packaging
Film-Coated Tablet 1's
Generic Name
Betahistine Hydrochloride
Registration Number
DR-XY42321
Classification
Prescription Drug (RX)
Product Questions
Questions
