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Indications
Use in the treatment of rheumatoid arthritis including juvenile idiopathic arthritis, osteoarthritis, and ankylosing spondylitis, and in the adjunctive treatment of adenomatous colorectal polyps. It is also used in the management of acute pain and dysmenorrheas.
Administration
May be taken with or without food.
Contraindication
Hypersensitivity to celecoxib, aspirin, sulfonamides or other NSAIDs. History of asthma, urticaria, acute rhinitis, nasal polyps, angioneurotic oedema or other allergic-type reactions after taking aspirin or other NSAIDs. Active peptic ulceration or gastrointestinal bleeding, inflammatory bowel disease, CHF (NYHA II-IV), established ischaemic heart disease, cerebrovascular disease or peripheral arterial disease. Use in the setting of CABG surgery. Severe renal (CrCl <30 mL/min) and hepatic (Child-Pugh class C or ≥10 score) impairment. Pregnancy and lactation.
Special Precaution
Patient with history of gastrointestinal complications (e.g. ulceration and bleeding), hypertension, diabetes mellitus, hyperlipidaemia, recent MI, and other CV disease risk factors (e.g. smoking, alcoholism); pre-existing asthma (without known aspirin sensitivity), pre-existing oedema, hypovolaemia. Dehydrated patient. May mask underlying fever and other signs of inflammation. Not indicated for the preventive treatment of migraine. CYP2C9 poor metabolisers. Mild to moderate renal and moderate hepatic impairment. Children and elderly.
Storage
Store below 30°C.
MedsGo Class
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Features
Brand
Saphlecox-400
Full Details
Dosage Strength
400 mg
Drug Ingredients
- Celecoxib
Drug Packaging
Capsule 100's
Generic Name
Celecoxib
Dosage Form
Capsule
Registration Number
DRP-9808
Drug Classification
Prescription Drug (RX)