All variations
Indications/Uses
For primary prevention of thromboembolic disorders and cardiovascular events: Ischemic stroke; Transient ischemic attack (TIA); Acute myocardial infarction (MI).
Aspilets: Prevention of recurrent MI; Unstable angina pectoris; Chronic stable angina pectoris.
For secondary prevention of cardiovascular disease in persons with diabetes mellitus especially in the following subgroups: History of myocardial infarction, vascular bypass procedure, stroke or transient ischemic attack, and angina.
Persons with additional risk factors: hypertension, smoking, dyslipidemia, and family history of cardiovascular disease.
Revascularization Procedures: For patients who have undergone revascularization procedures such as coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA), and carotid endarterectomy when there is a pre-existing condition for which aspirin is already indicated.
Pregnancy-Induced Hypertension: For primary prevention of pregnancy-induced hypertension, preeclampsia and intrauterine growth retardation particularly in pregnant women with pre-existing chronic hypertension, auto-immune disorders like systemic lupus erythematosus (SLE), positive anticardiolipin antibody test, history of recurring toxemia in successive pregnancies, and hypotension developing before the 20th week of gestation.
Aspilets EC: For the prevention of cardiovascular disease: Encourage aspirin use in men (age 45 to 79 years old) and women (age 55 to 79 years old) when potential benefit (i.e., prevention of myocardial infarction in men and prevention of ischemic stroke in women) outweighs potential harm of gastrointestinal hemorrhage.
Aspilets: Prevention of recurrent MI; Unstable angina pectoris; Chronic stable angina pectoris.
For secondary prevention of cardiovascular disease in persons with diabetes mellitus especially in the following subgroups: History of myocardial infarction, vascular bypass procedure, stroke or transient ischemic attack, and angina.
Persons with additional risk factors: hypertension, smoking, dyslipidemia, and family history of cardiovascular disease.
Revascularization Procedures: For patients who have undergone revascularization procedures such as coronary artery bypass graft (CABG), percutaneous transluminal coronary angioplasty (PTCA), and carotid endarterectomy when there is a pre-existing condition for which aspirin is already indicated.
Pregnancy-Induced Hypertension: For primary prevention of pregnancy-induced hypertension, preeclampsia and intrauterine growth retardation particularly in pregnant women with pre-existing chronic hypertension, auto-immune disorders like systemic lupus erythematosus (SLE), positive anticardiolipin antibody test, history of recurring toxemia in successive pregnancies, and hypotension developing before the 20th week of gestation.
Aspilets EC: For the prevention of cardiovascular disease: Encourage aspirin use in men (age 45 to 79 years old) and women (age 55 to 79 years old) when potential benefit (i.e., prevention of myocardial infarction in men and prevention of ischemic stroke in women) outweighs potential harm of gastrointestinal hemorrhage.
Dosage/Direction for Use
Take each dose of aspirin with a full glass of water unless patient is fluid restricted.
Aspirin maintenance should be initiated once hyOr as prescribed by the physician.
Aspilets-EC: The tablet must be swallowed whole with a glass of water. Do not chew, crush, or bite the enteric-coated tablet since this may cause inappropriate release and absorption of the drug.ertension is controlled.
Aspirin maintenance should be initiated once hyOr as prescribed by the physician.
Aspilets-EC: The tablet must be swallowed whole with a glass of water. Do not chew, crush, or bite the enteric-coated tablet since this may cause inappropriate release and absorption of the drug.ertension is controlled.
Overdosage
In salicylate overdosage resulting from acute ingestion of aspirin, little or no toxicity generally occurs in individuals ingesting less than 150 mg/kg, mild to moderate toxicity in those ingesting 150 to 300 mg/kg, severe toxicity in those ingesting 300 to 500 mg, and potentially lethal toxicity in those ingesting greater than 500 mg/kg. A single lethal dose of aspirin in adults is not known with certainty but death may be expected at 30 g.
The principal toxic effects of salicylate overdosage are extension of pharmacologic actions and include local gastrointestinal irritation, direct central nervous system stimulation of respiration, severe acid-base and electrolyte disturbances and are complicated by hyperthermia and dehydration. Respiratory alkalosis occurs early while hyperventilation is present, but is quickly followed by metabolic acidosis.
Treatment consists primarily of supporting vital functions, increasing salicylate elimination, and correcting the acid-base disturbance. Gastric emptying and/or lavage is recommended as soon as possible after ingestion, even if the patient has vomited spontaneously. After lavage and/or emesis, administration of activated charcoal (as a slurry), is beneficial, if less than 3 hours have passed since ingestion. Charcoal adsorption should not be employed prior to emesis and lavage.
Severity of aspirin intoxication is determined by measuring the blood salicylate level. Acid-base status should be closely followed with serial blood gas and serum pH measurements. Fluid and electrolyte balance should be maintained.
Hemodialysis and peritoneal dialysis may be performed to reduce the body drug content. Dialysis is usually required in patients with renal insufficiency or in cases of life-threatening intoxication.
The principal toxic effects of salicylate overdosage are extension of pharmacologic actions and include local gastrointestinal irritation, direct central nervous system stimulation of respiration, severe acid-base and electrolyte disturbances and are complicated by hyperthermia and dehydration. Respiratory alkalosis occurs early while hyperventilation is present, but is quickly followed by metabolic acidosis.
Treatment consists primarily of supporting vital functions, increasing salicylate elimination, and correcting the acid-base disturbance. Gastric emptying and/or lavage is recommended as soon as possible after ingestion, even if the patient has vomited spontaneously. After lavage and/or emesis, administration of activated charcoal (as a slurry), is beneficial, if less than 3 hours have passed since ingestion. Charcoal adsorption should not be employed prior to emesis and lavage.
Severity of aspirin intoxication is determined by measuring the blood salicylate level. Acid-base status should be closely followed with serial blood gas and serum pH measurements. Fluid and electrolyte balance should be maintained.
Hemodialysis and peritoneal dialysis may be performed to reduce the body drug content. Dialysis is usually required in patients with renal insufficiency or in cases of life-threatening intoxication.
Administration
Should be taken with food: Take immediately after meals w/ a full glass of water unless patient is fluid-restricted. Aspilets-EC tab: Swallow whole, do not chew/crush/bite.
Contraindications
Known hypersensitivity to aspirin.
Patients with asthma, rhinitis, and nasal polyps. Aspirin may cause severe urticaria, angioedema, or bronchospasm.
Avoid use in children or teenagers for viral infections, with or without fever, because of the risk of Reye's syndrome with concomitant use of aspirin in certain viral illnesses.
Patients with asthma, rhinitis, and nasal polyps. Aspirin may cause severe urticaria, angioedema, or bronchospasm.
Avoid use in children or teenagers for viral infections, with or without fever, because of the risk of Reye's syndrome with concomitant use of aspirin in certain viral illnesses.
Features
Dosage
80mg
Ingredients
- Aspirin
Packaging
Enteric-Coated Tablet 1's
Generic Name
Aspirin
Registration Number
DRP-9977
Classification
Prescription Drug (RX)
Product Questions
Questions
