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PROSTAZIN Tamsulosin Hydrochloride 400mcg Enteric-Coated Tablet 30's

RXDRUG-DRP-4938-02
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Description

Indications/Uses

It is used in benign prostatic hyperplasia to relieve symptoms of urinary obstruction.
 

Dosage/Direction for Use

In benign prostatic hyperplasia, Tamsulosin Hydrochloride is given by mouth in a modified-release formulation, in a dose of 400 micrograms once daily. Swallow whole tablet with glass of water, 30 mins after meal. Or as directed by the physician.
 

Administration

Should be taken with food: Take 30 min after meal. Swallow whole w/ a glass of water.
 

Contraindications

Used with caution in severely decreased kidney function.
Not to be used in history of drops in blood pressure when moving from sitting or lying position to standing, which causes dizziness (postural hypotension) severely decreased liver function. This medicine should not be used if the patient is allergic to one or any of its ingredients. Please inform the doctor or pharmacist if the patient has previously experienced such an allergy. If the patient has experienced an allergic reaction stop using this medicine and inform the doctor or pharmacist immediately.
 

Special Precautions

This medicine may cause dizziness, lightheadedness on rare occasions fainting. Take care when moving from a lying down or sitting or standing particularly when the patient wakes up in the night, until the patient knows how this medicine affects him/her. If the patient feels dizzy or lightheaded at any time during treatment, sit or lie down until the symptoms pass.
This medicine may cause drowsiness, dizziness or blurred vision and so may affect the ability to drive or operate machinery safely. Do not drive or operate machinery until the patient knows how this medicine affects him/her and the patient is sure it won't affect his/her performance.
This medicine does not cause prostate cancer but prostate cancer can be another cause of an enlarged prostate gland.
For this reason tests for prostate cancer should be carried out before the patient starts treatment with this medicine and at regular intervals thereafter.
One test that can be carried out is a digital rectal examination (DRE). The other is to measure the level of prostate specific antigen (PSA) in the blood.
If the patient is scheduled to have eye surgery or cataract it is important to let the eye specialist know if the patient is or has been taking this medicine. This is because Tamsulosin can make the pupil dilate poorly and the iris (the coloured circular part of the eye) become floppy during the procedure. The specialist needs to know if the patient has been taking this medicine so they can take appropriate precautions with the medicines and techniques they use during the surgery. The patient may be asked to stop taking this medicine for a period of time before cataract surgery. Check with the doctor.
 

Adverse Reactions

Medicines and their possible adverse effects affect individual people in different ways. The following are some of the adverse effects that are known to be associated with this medicine. Simply because an adverse effect is stated here, it does not mean that all people using this medicine will experience that or any adverse effect.
Dizziness; Headache; Weakness or loss of strength (asthenia); Abnormal ejaculation; A drop in blood pressure that occurs when going from lying down to sitting or standing, which results in dizziness and lightheadedness (postural hypotension); Fainting (syncope); Awareness of the heartbeat (palpitations); Disturbances of the gut such as diarrhoea, constipation, nausea or vomiting; Inflammation of the lining of the nose (rhinitis) causing a blocked or runny nose; Skin reactions such as rash and itch; Drowsiness; Blurred vision; Dry mouth; Swelling due to fluid retention (oedema); Persistent painful erection of the penis (priapism).
 

Drug Interactions

It is important to tell the doctor or pharmacist what medicines the patient is already taking including those bought without a prescription and herbal medicines before starting treatment with this medicine. Similarly check with the doctor or pharmacist before taking any new medicines while taking this one to ensure that the combination is safe.
If this medicine is taken with other medicines that can reduce blood pressure this effect may be enhanced with an increased chance of dizziness or fainting. Other medicines that may reduce blood pressure include the following: anaesthetics; medicines for high blood pressure; other alpha blockers; phosphodiesterase type 5 inhibitors for impotence, e.g., sildenafil, vardenafil, tadalafil.
 

Storage

Store at temperatures not exceeding 30°C.
 

Action

Pharmacology: Pharmacokinetics: Tamsulosin is absorbed from the gastrointestinal tract and is almost completely bioavailable. The extent and rate of absorption are reduced in the presence of food. Following oral administration of an immediate release preparation, peak plasma concentrations occur about 1 hour after a dose. Tamsulosin is metabolized slowly in the liver and is excreted mainly in the urine as metabolites and some unchanged drug. The plasma elimination half-life has been reported to be between 4 and 5.5 hours. Tamsulosin is about 99% bound to plasma proteins.
 

MedsGo Class

Drugs for Bladder & Prostate Disorders

Features

Brand
Prostazin
Full Details
Dosage Strength
400 mcg
Drug Ingredients
  • Tamsulosin
Drug Packaging
Enteric-coated Tablet 30's
Generic Name
Tamsulosin Hydrochloride
Dosage Form
Enteric-Coated Tablet
Registration Number
DRP-4938-02
Drug Classification
Prescription Drug (RX)
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