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Features
- Sildenafil
Description
Why it's used
Spiagra-100 Tablet is used to treat the inability to keep an enlarged and rigid state of the penis during sexual activity. This condition is known as erectile dysfunction or ED. It is a prescription medicine. This medicine helps by relaxing muscles and therefore allowing the flow of blood into the penis. This helps a man to keep the penis in an enlarged and rigid state during sexual excitement.
Phosphodiesterase 5 Inhibitors
Spiagra-100 belongs to a class of medicines called Phosphodiesterase 5 Inhibitors. Phosphodiesterase 5 (PDE5) inhibitors are a group of targeted therapy medicines that used to treat people with high blood pressure. PDE 5 inhibitors are also used to treat erectile dysfunction.
How to use
Follow directions on the product label, information guide, and provided by your doctor before using Spiagra-100. Eat this medicine as per your doctor's instructions.
Spiagra-100 is eaten with or without food. Avoid taking this medicine with the high-fat meal as it may reduce the effectiveness of the medicine. Spiagra-100 is eaten around 1 hour before sexual activity. Spiagra-100 is not effective in the absence of sexual arousal.
Typical Dosage
The typical adult dose of Spiagra-100 is 50 mg once a day (not more than 100 mg in one day). The maximum dose for adults of Spiagra-100 is 100 mg per day. It takes 1 hour for this medicine to start its action. There are no known habit-forming tendencies with this medicine.
This medicine should be used on an as-needed basis.
Talk to Your Doctor
Tell your doctor if you develop new or worsening symptoms. Talk to your doctor if decreased blood pressure, chest pain, nausea, dizziness, decrease or loss of hearing, have an erection lasting more than 4 hours, and have loss of vision in one or both eyes. If you have any kidney disease, a lower dose will be prescribed. If you have issues with the health of your liver, a lower dose will be prescribed by the doctor.
To see the impact of Spiagra-100 Tablet on the body, your doctor may recommend a lower initial dose. Please follow your doctor's instructions carefully. Taking a high dose of this medicine is known to increase the chances of side-effects. A lower dose of Spiagra-100 Tablet may be recommended to reduce the risk of side-effects. Older patients may see an increase in the risk of side-effects. Hence, a lower dose may be recommended.
Use in Children
The safety and effectiveness of using this medicine in children has not been established.
Possibly safe with Alcohol
Spiagra-100 is known to be safe while drinking alcohol.
Storage
Store Spiagra-100 Tablet store at 15-30°C (59-86°F) temperature, away from excess moisture, and away from light. Keep this medicine away from children and pets.
Medicines may be given for uses other than those listed in the medicine guide. Do not use Spiagra-100 Tablet for symptoms for which it was not prescribed. Do not give Spiagra-100 Tablet to others who may have similar symptoms as you. Self-medication can cause harm.
How to take Spiagra-100
Your dose and how often you take Spiagra-100 will depend on the following factors:
- age
- patient's health
- the health of the patient's liver
- the health of the patient's kidneys
- medicines recommended by the doctor
- any other medicines being used
- response to the medicine
Spiagra-100 Dosage
Dosage for erectile dysfunction
Adult
- Recommended: 50 mg per day
- Initial: 25 mg per day
- Maximum: 100 mg per day
Older Adults (65 years or higher)
- Recommended: 50 mg/day
- Initial: 25 mg/day
- Maximum: 100 mg/day
Minimum Age
- 18 years
Forms
- Tablet
- Strength: 25 mg, 50 mg and 100 mg
Special Instructions
Oral formulations
- Use not more than one tablet in a day with or without meals.
Overdose
What to do if you overdose on Spiagra-100?
In case of overdose, standard supportive measures should be adopted.
Precautions while using Spiagra-100
Before you use Spiagra-100, tell your doctor of your medical and health history including the following:
- bleeding disorder
- blood circulation problems
- cancer of blood cells (leukemia)
- cancer of white blood cells (multiple myeloma)
- chest pain (angina)
- deformed penis shape
- diabetes
- eye disease
- have had blockage of veins in the lungs (PVOD)
- heart failure
- high blood pressure
high cholesterol - history of heart surgery
- kidney or liver disease
- low blood pressure
- palpitation
- recently have had dehydration
- red blood cells disorder (sickle cell anemia)
- rigid state of the penis that lasts for more than 4 hours during sexual excitement (priapism)
- severe vision loss
- stomach ulcers
- stroke
Before you use Spiagra-100, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information.
The use of Spiagra-100 Tablet may change blood pressure. Patients with known history of heart disease or stroke should monitor their blood pressure.
Use when Pregnant
Spiagra-100 is not for use by women. Hence women who are pregnant should not use this medicine.
If Breastfeeding
Women who are breastfeeding should not use this medicine.
Alcohol
Spiagra-100 is known to be safe while drinking alcohol.
Seizures
Spiagra-100 can make you feel sleepy. Be careful, especially while driving, while using heavy machinery, or when doing any activity that needs you to be completely alert. The consumption of alcohol with Spiagra-100 can worsen the sleepiness. Spiagra-100 may cause seizures in some people. Hence, you should discuss with your doctor before performing any activities where a loss of consciousness may cause harm to you or others.
Side-effects in Older Patients
Older patients may have a higher incidence of side-effects when using Spiagra-100 Tablet.
What precautions should be taken during Pregnancy and Nursing, and administering Spiagra-100 to Children or the Older Adults?
Pregnant Women
Contraindicated or Not Recommended
Warning: This medicine is not recommended for use in pregnant women.
Breastfeeding
Contraindicated or Not Recommended
Warning: This medicine is not recommended for use during breastfeeding.
Younger Adults Population
Contraindicated or Not Recommended
Warning: This medicine is not recommended for children.
Older Adults Population
Possibly Safe
Warning: A starting dose of 25 mg should be considered for older patients greater than 65 years.
Spiagra-100 Side-effects
The following side-effects may commonly occur when using Spiagra-100 Tablet. If any of these side-effects worsen or last for a long time, you should consult with your doctor:
- abnormal vision
- back pain
- blurred vision
- changes in color vision
- dizziness
- headache
- muscle pain
- nausea
- rash
- skin flushing
- stuffy or a runny nose
- upset stomach
The following severe side-effects may also occur when using Spiagra-100 Tablet:
- Erections lasting more than 4 hours (known as, priapism) (permanent injury to the penis)
Symptoms: painfully enlarged and rigid state of the penis for more than 4 hours
If this happens, you should contact your doctor right away. - Sudden vision loss in one or both eyes
The medicine should be discontinued and you should contact your doctor right away. - Heart disease (palpitation, or heart attack) (possibly fatal)
If this happens, contact your doctor right away and stop taking medicine. - Sudden loss or decrease in hearing
Symptoms: dizziness ringing in the ears
The medicine should be discontinued and you should contact your doctor right away.
Your doctor has prescribed Spiagra-100 Tablet because they judge that the benefit is greater than the risk posed by side-effects. Many people using this medicine do not have serious side-effects. This page does not list all possible side-effects of Spiagra-100 Tablet.
Side-effects and Allergic Reactions of Spiagra-100 by Severity and Frequency
Common Side-effects
Following are the common side-effects of this medicine:
- abnormal vision
- back pain
- blurred vision
- changes in color vision
- dizziness
- flushing
- headache
- muscle pain
- nausea
- rash
- stuffy or a runny nose
- upset stomach
Severe Side-effects
Following are the severe side-effects of this medicine:
- enlarged and rigid state of the penis occurring during sexual excitement that lasts many hours (priapism)
- heart attack
- palpitation
- stroke
- sudden hearing decrease or hearing loss
- sudden vision loss in one or both eyes
Mild Allergic Reactions
Following are the symptoms of mild allergic reactions to this medicine:
- hives
- rash
Consult with your doctor.
Warnings
Other Erectile Dysfunction Medicines
The combined use of Spiagra-100 with other erectile dysfunction medicines may result in further lowering of the blood pressure. Combined use of multiple erectile dysfunction medicines is not recommended.
Use of Ritonavir
In patients using Spiagra-100 along with Ritonavir, it can result in decreased blood pressure, loss of consciousness, and prolonged erection. For such patients, lower dosage of Spiagra-100 is recommended.
Low Blood Pressure
In patients using low blood pressure medicines and Spiagra-100 together, the blood pressure can drop significantly. This can result in dizziness, lightheadedness, and fainting. Such patients should first establish a stable regimen for their low blood pressure medicines and then start at a lower dose for Spiagra-100.
Prolonged Erection
Some patients may have a prolonged erection lasting more than 4 hours, or a painful erection lasting more than 6 hours. In this happens, you should consult with your doctor immediately.
Existing Heart Disease
Patients with any prior history of heart diseases may have a higher risk of heart attack. Such patients should use this medicine with caution.
Loss of Hearing
Usage of this medicine may cause a sudden decrease or loss of hearing, ringing in ears (tinnitus), and dizziness. If you experience any of these symptoms, you should should stop the use of the medicine.
Non-Arteritic Anterior Ischemic Optic Neuropathy
Patients with NAION (non-arteritic anterior ischemic optic neuropathy) risk factors may face a sudden loss of vision in one or both eyes. This medicine should be used with caution and if a loss of vision occurs, the medicine should be discontinued.
Interactions with Spiagra-100
When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
This page does not contain all the possible interactions of Spiagra-100 Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.
Calcium Channel Blockers
Spiagra-100 Tablet interacts with amlodipine, which is a medicine used to lower the blood pressure. Taking these two drugs together can result in an abnormal blood pressure. As a result, Amlodipine and Spiagra-100 should be used together with caution.
Alpha-Blockers
There may be an interaction of Spiagra-100 with alpha-blockers, which are medicines used to lower the blood pressure and treat prostate enlargement in men. Using Spiagra-100 with alpha-blockers can result in reduced blood pressure. In such cases, the patient should be given the lowest dose of Spiagra-100, which is 25 mg.
Nitrates
Spiagra-100 Tablet may interact with organic nitrates or nitrites, which are used to treat chest pain and heart disease. Using Spiagra-100 along with nitrates can result in harmful effects on the heart. Hence, organic nitrates or nitrites should not be used in combination with this medicine.
CYP3A4 Inhibitors
Special instructions need to be followed while taking this medicine along with ritonavir and other CYP3A4 inhibitors, which are medicines used in the treatment of HIV/AIDS. When these two drugs are given together, CYP3A4 inhibitors cause the levels of Spiagra-100 in the blood to increase several folds. A starting dose of 25 mg of Spiagra-100 should be considered in patients taking CYP3A4 inhibitors.
Interactions of Spiagra-100 by Severity
Severe
The following medicines are usually not to be taken together without consulting with your doctor or pharmacist.
- nitrates
Serious
The following medicines may interact when taken together and can cause harmful effects in the body. Please consult with your doctor or pharmacist before taking these medicines together.
- Amlodipine
Moderate
The following medicines may interact when taken together and can increase your risk of harmful effects. Please consult with your doctor or pharmacist before taking these medicines together.
- Ritonavir
- Alpha-Adrenergic Blocker
When should Spiagra-100 be not used?
Allergic Reactions
This medicine should not be used in patients who are allergic to it. These patients may have the following symptoms if they use this medicine:
- rash
- hives
Nitrates, Used to Treat Angina
This medicine should not be used by patients who are taking organic nitrates or organic nitrites. This medicine should not be given with nitrates in any form due to its hypotensive effects.