Indications / Uses
TRAJENTA DUO Linagliptin / Metformin 2.5mg / 850mg is used for improving blood sugar control in adults with type 2 diabetes mellitus, used alongside a dedicated diet and exercise plan. It is appropriate when control is inadequate with metformin alone, or in patients already stable on the two individual components. It can also be used as part of a triple combination regimen with a sulfonylurea, an SGLT2 inhibitor, or as an addition to existing insulin therapy.
Formulation / Ingredients
TRAJENTA DUO Linagliptin / Metformin 2.5mg / 850mg contains: Linagliptin 2.5mg + Metformin Hydrochloride 850mg
Do I need prescription to buy TRAJENTA DUO Linagliptin / Metformin 2.5mg / 850mg?
Yes, you need a prescription. But if you don't have one, you can get a free teleconsultation from MedsGo Physician. Just make an order and our Physician will call you back.
Side Effects
TRAJENTA DUO Linagliptin / Metformin 2.5mg / 850mg common side effects include: cold-like symptoms such as a sore throat or stuffy nose, along with gastrointestinal discomfort like diarrhea, nausea, or vomiting. A serious, though rare, risk is the accumulation of lactic acid in the blood, which may present as unusual muscle pain, trouble breathing, or extreme weakness. Other reported reactions include inflammation of the pancreas, severe and disabling joint pain, and hypersensitivity reactions such as hives and skin blistering.
Directions and Dosage
- Dosage for Adults (18+ years): This medication is typically administered twice daily with meals.
- The maximum total daily intake is 5 mg of the first component (linagliptin) and 2000 mg of the second component (metformin).
- Age Restriction: Not recommended for individuals under 18 years of age due to lack of established safety and efficacy data.
Contraindications
The drug is not suitable for individuals with:
- Severe kidney impairment or kidney failure.
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
- Severe liver disease or significant hepatic impairment.
- Known hypersensitivity to either of the two primary active components or any inactive ingredients.
Use in Pregnancy and Lactation
The use of this medication during pregnancy is generally not recommended as there is a definite evidence of risk to the developing baby. Data suggests that using the drug while breastfeeding may cause toxicity to the nursing individual.
Special Precautions
- Risk of a dangerous buildup of acid in the blood, particularly in the presence of kidney problems, severe infection, or heart failure.
- Temporary discontinuation may be required around the time of an imaging procedure using iodinated contrast agents.
- Caution should be exercised if there is a history of inflammation of the pancreas.
- Regular monitoring of kidney function is essential before and during administration.
- There is a possibility of developing severe and disabling discomfort in the joints.
- May cause low levels of Vitamin B12.
Is it safe to take it with other medications?
Care is advised when taken with other glucose-lowering drugs like sulfonylureas or insulin, as this increases the risk of low blood sugar, which may require a dose reduction of the other medication. Some antibiotics, such as rifampin, can reduce the effectiveness of the first component. Alcohol consumption should be avoided as it increases the risk of lactic acid accumulation.
How should I store it?
Keep the tablets in the original packaging. Store the product in a cool, dry place, ensuring it is kept away from moisture and heat.
Used For
- Type 2 Diabetes
Age
- Adults (18+ years)
Features
- Linagliptin
- Metformin
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