TWYNSTA Telmisartan / Amlodipine 40mg / 5mg - 1 Tablet

Indications / Uses

TWYNSTA Telmisartan / Amlodipine 40 / 5 is used for the management of high blood pressure, also known as essential hypertension. It is a fixed-dose combination product intended for individuals whose blood pressure is not adequately controlled by either telmisartan or amlodipine alone. This combination may also be used as an initial therapy in individuals who are likely to require multiple medications to achieve their target blood pressure goals. By combining two active components, it provides a dual mechanism of action to help achieve better blood pressure control and reduce the risk of cardiovascular events.

Formulation / Ingredients

TWYNSTA Telmisartan / Amlodipine 40 / 5 contains: Telmisartan 40mg + Amlodipine 5mg

Side Effects

TWYNSTA Telmisartan / Amlodipine 40 / 5 common side effects include: swelling of the hands or feet (peripheral edema), dizziness, and back pain. Other possible effects may involve a drop in blood pressure, drowsiness, and flushing (a feeling of warmth or redness). Less frequent effects reported include nausea, diarrhea, stomach pain, and a pounding or fast heartbeat. Symptoms like new or worsened chest pain, unexplained muscle pain, or a light-headed feeling may require immediate attention.

Directions and Dosage

• Dosage for Adults (18+ years): The usual starting dose is 40 mg / 5 mg once daily.
• The dose may be increased after at least 2 weeks of therapy to a maximum of 80 mg / 10 mg once daily.

This product is not recommended for use in individuals under 18 years old. For individuals over 75 years of age, initial therapy with this combination is not recommended; a lower starting dose of the amlodipine component should be considered if used.

Contraindications

The product should not be used in individuals with a known hypersensitivity to the components or to dihydropyridine derivatives. It is also contraindicated during the second and third trimesters of pregnancy. Do not use this product concomitantly with aliskiren in individuals with diabetes.

Use in Pregnancy and Lactation

Use during the second and third trimesters of pregnancy is strictly contraindicated due to the risk of fetal harm. Discontinuing the product is required if pregnancy is detected. Use while breastfeeding is not recommended due to the potential for serious adverse effects in the breastfed infant.

Special Precautions

• Monitor for potential worsening of heart failure.
• Exercise caution and titrate slowly in individuals with liver impairment or severe kidney impairment.
• Correct any low blood volume or low salt levels before starting treatment.
• Severe obstructive coronary artery disease may increase the risk of a heart event upon initiation or dose increase.

Is it safe to take it with other medications?

Using it with other agents that lower blood pressure may result in an excessive decrease in blood pressure. Avoid co-administration with aliskiren in diabetic individuals. Use with non-steroidal anti-inflammatory agents requires caution due to an increased risk of kidney impairment and potential loss of the blood pressure-lowering effect.

How should I store it?

Store at temperatures not exceeding 30°C. Keep the tablets in the sealed blister packaging until immediately before use to protect them from moisture.

Used For

High Blood Pressure

Age

18 years & up