BIOZART DUO Losartan / Amlodipine 50mg / 5mg - 1 Tablet

Indications / Uses

BIOZART DUO Losartan / Amlodipine 50 / 5 is used for the treatment of essential **hypertension**, commonly known as high blood pressure. This dual-action medication is often utilized when blood pressure is not adequately controlled with either a Calcium Channel Blocker or an Angiotensin II Receptor Antagonist alone. It effectively works by combining two different mechanisms to lower blood pressure, helping to reduce the risk of cardiovascular events. The combination provides sustained blood pressure management throughout the day.

Formulation / Ingredients

BIOZART DUO Losartan / Amlodipine 50 / 5 contains: Losartan Potassium 50mg + Amlodipine 5mg

Side Effects

BIOZART DUO Losartan / Amlodipine 50 / 5 common side effects include: **dizziness, headache, fatigue, and peripheral edema** (swelling of the ankles or feet). Less frequently observed effects may involve mild gastrointestinal discomfort, flushing, or lightheadedness, especially upon standing up too quickly. The combination of ingredients generally aims to provide the benefits of both agents while minimizing potential dose-related reactions. Serious adverse reactions are uncommon but necessitate immediate attention.

Directions and Dosage

• Adults (18+ years): The usual recommended daily intake is 1 tablet. The maximum daily dosage for this specific formulation is 1 tablet.
• Adolescents and Children: The use of this combination formulation is generally not recommended for individuals under 18.

Contraindications

Contraindications include a known history of **hypersensitivity** or allergic reaction to either of the components or any related substance. It should not be used in cases of severe **low blood pressure** or cardiogenic shock. Use is generally avoided in patients with a history of **angioedema** related to the use of similar blood pressure regulating substances.

Use in Pregnancy and Lactation

Drugs that act on the renin-angiotensin system, like the component in this product, can cause serious harm to a developing human. Use is considered especially dangerous during the **second and third trimesters**. It should not be used if pregnancy is detected.

Special Precautions

• Requires careful administration in individuals who are prone to a sudden drop in blood pressure, such as those with fluid depletion.
• Use requires extra caution in individuals with impaired liver function or pre-existing severe kidney impairment.
• The combination may affect electrolyte levels, requiring periodic monitoring.

Is it safe to take it with other medications?

Avoid co-administration with other substances that increase potassium levels, as this may lead to high blood potassium. Combining it with other strong pressure-lowering agents may lead to dangerously low blood pressure. Use with certain non-steroidal pain relievers may reduce its effectiveness.

How should I store it?

Store the tablets in the original blister pack at temperatures **not exceeding 30°C**. Keep the product protected from light and moisture to maintain its stability.

Used For

Hypertension

Age

Adults (18+ years)