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SIMECO Hydrotalcite / Magnesium Hydroxide / Dimethicone 282mg / 85mg / 25mg Tablet 1's

NONRXDRUG-DR-XY26316-1pc
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Features

Brand
Simeco
Full Details
Dosage Strength
282 mg / 85 mg / 25 mg
Drug Ingredients
  • Dimethicone
  • Hydrotalcite
  • Magnesium
Drug Packaging
Tablet 1's
Generic Name
Dimethicone / Hydrotalcite / Magnesium
Dosage Form
Tablet
Registration Number
DR-XY26316
Drug Classification
Over-The-Counter (OTC)
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Description

Indications/Uses

This medicine is indicated for the symptomatic relief of hyperacidity and flatulence associated with the diagnosis of peptic ulcer, gastritis, gastroesophageal reflux esophagitis, hyperacidity, and hiatal hernia and dyspeptic complaints.
 

Dosage/Direction for Use

Adults: 2-4 chewable tablets taken 1-2 hours after meals and at bedtime or as directed by a physician. Tablets should be chewed.
Missed Dose: If the doctor has told the patient to take the medication regularly, take the missed dose as soon as the patient remembers it. However, if it is almost time for the next dose, skip the missed dose and continue the regular dosing schedule. Do not take double dose to make up for the missed one.
 

Overdosage

Signs and symptoms include nausea and vomiting and muscle weakness. Severe toxicity occurs after chronic excessive oral doses, often in patients with renal insufficiency. Early manifestations are lethargy, hyporeflexia (decrease reflexes) followed by weakness, paralysis, hypotension, ECG changes (prolonged PR and QRS intervals), CNS depression, seizures and respiratory depression.
In case of accidental overdose or at the first sign of any adverse reaction, discontinue use and seek professional assistance immediately.
 

Administration

Should be taken on an empty stomach: Take 1-2 hr after meals & at bedtime. Tab should be chewed.
 

Contraindications

This product is contraindicated for use in patients with: Known hypersensitivity to the active ingredients or any other components listed in Description.
Severe renal impairment and abdominal pain.
 

Special Precautions

The recommended dose should not be exceeded without medical advice.
In renal failure and long term use in particular, there is an increased risk of phosphate depletion syndrome with hypercalciuria and osteomalacia or aluminum ion-induced deterioration in dementia syndrome in patients receiving chronic renal dialysis.
Caution is also required in individuals with severe constipation, especially elderly ones, or following a low-sodium diet.
When there is a need for other medicines, these may be taken at two-hour intervals.
Use in Pregnancy: There are no adequate clinical studies in pregnant women. However, aluminum and magnesium-containing antacids are generally considered safe for use during the last two trimesters of pregnancy as long as chronic high doses are avoided. Problems with Dimethicone use have not been documented during all three trimesters of pregnancy.
Use in Lactation: There is no evidence to suggest that Dimethicone, aluminum and magnesium-containing antacids should not be given to breast feeding mothers.
Consult the Doctor: If the patient notices other side effects that the he/she thinks are caused by this medicine, tell the doctor.
 

Use In Pregnancy & Lactation

Use in Pregnancy: There are no adequate clinical studies in pregnant women. However, aluminum and magnesium-containing antacids are generally considered safe for use during the last two trimesters of pregnancy as long as chronic high doses are avoided. Problems with Dimethicone use have not been documented during all three trimesters of pregnancy.
Use in Lactation: There is no evidence to suggest that Dimethicone or aluminum and magnesium-containing antacids should not be given to breastfeeding mothers.
 

Adverse Reactions

Magnesium-containing and Aluminum containing antacids usually do not cause constipation or diarrhea. This medication may rarely cause nausea or vomiting and very rarely, during long-term use, development of phosphate depletion syndrome or formation of fecaliths in elderly patients with severe constipation.
 

Drug Interactions

The concurrent use of the product with tetracyclines may inhibit their absorption (except for Doxycycline and possibly minocycline). The absorption of other medicines (anticholinergics, cimetidine, isoniazid, triazole antifungals iron salts, carbenoxolone, digitoxin, quinidine, phenobarbital) may also be delayed or reduced, or warfarin and phenindione absorption may be impaired.
The concurrent use of this product with the following agents decreases their effect: Benzodiazepines, captopril, corticosteroids, fluoroquinolones, H2 histamine receptor antagonists, hydantoins, ketoconazole, penicillamine, phenothiazines, salicylates and ticlopidine.
On the contrary, the concurrent use of this product with the following agents increases their effect: Levodopa, sulfonylureas and sodium valproate.
Acetate salts increase the adsorption and hence the toxicity of aluminum ions. With the ion-exchange resin, sodium polystyrene sulfonate, it may cause metabolic alkalosis in patients with renal failure. Antacids should not be administered in combination with the above products. These other medical products should be taken at least 1 to 2 hours before the antacids.
 

Storage

Store at temperatures below 30°C.
 

MedsGo Class

Antacids, Antireflux Agents & Antiulcerants
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