BIOFLU Phenylephrine Hydrochloride / Chlorphenamine Maleate / Paracetamol 10mg / 2mg / 500mg Tablet 1's
NONRXDRUG-DR-XY34482-1pc
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Features
Brand
Bioflu
Full Details
Dosage Strength
10mg / 2mg / 500mg
Drug Ingredients
- Chlorphenamine Maleate
- Paracetamol
- Phenylephrine Hcl
Drug Packaging
Tablet 1's
Generic Name
Phenylephrine Hcl / Chlorphenamine Maleate / Paracetamol
Dosage Form
Tablet
Registration Number
DR-XY34482
Drug Classification
Over-The-Counter (OTC)
Description
Indications/Uses
Used for the relief of clogged nose, runny nose, postnasal drip, itchy and watery eyes, sneezing, headache, body aches, and fever associated with flu, the common cold, allergic rhinitis, sinusitis, and other minor respiratory tract infections. Help decongest sinus openings and passages.
Dosage/Direction for Use
Adults and Children 12 years and older: Orally (by mouth), 1 tablet/capsule every 6 hours, or as recommended by a doctor.
Missed Dose: If the patient missed a dose, just take the next dose if still needed for the condition being treated, and the subsequent doses at the recommended time or schedule (i.e., every 6 hours).
Do not double the dose.
Missed Dose: If the patient missed a dose, just take the next dose if still needed for the condition being treated, and the subsequent doses at the recommended time or schedule (i.e., every 6 hours).
Do not double the dose.
Overdosage
Signs and Symptoms: Phenylephrine HCl: Increased blood pressure, headache, seizures, palpitation, sensation of tingling, pricking or numbness of the skin (paresthesia), vomiting, and bleeding from a ruptured blood vessel in the brain (cerebral hemorrhage).
Chlorphenamine Maleate: Extreme sleepiness or prolonged drowsiness, convulsion, weakness, agitation, hallucination, irritability, tachycardia, and coma.
Paracetamol: Overdosage of Paracetamol usually involves 4 phases with the following signs and symptoms: Eating disorder, nausea, vomiting, malaise, and excessive sweating.
Right upper abdominal pain or tenderness, liver enlargement which may be characterized by abdominal discomfort of "feeling full", elevated bilirubin and liver enzyme concentrations, prolongation of prothrombin time, and occasionally decreased urine output.
Eating disorder, nausea, vomiting, and malaise recur and signs of liver (e.g., jaundice) and possibly kidney failure.
Recovery or progression to fatal complete liver failure.
Chlorphenamine Maleate: Extreme sleepiness or prolonged drowsiness, convulsion, weakness, agitation, hallucination, irritability, tachycardia, and coma.
Paracetamol: Overdosage of Paracetamol usually involves 4 phases with the following signs and symptoms: Eating disorder, nausea, vomiting, malaise, and excessive sweating.
Right upper abdominal pain or tenderness, liver enlargement which may be characterized by abdominal discomfort of "feeling full", elevated bilirubin and liver enzyme concentrations, prolongation of prothrombin time, and occasionally decreased urine output.
Eating disorder, nausea, vomiting, and malaise recur and signs of liver (e.g., jaundice) and possibly kidney failure.
Recovery or progression to fatal complete liver failure.
Administration
May be taken with or without food: May be given w/ food or milk if stomach upset occurs.
Contraindications
If the patient is allergic to any ingredient in the product.
If the patient has a history or is suffering from stomach ulcers, bleeding or other stomach problems.
If the patient has high blood pressure or severe heart disease unless recommended by a doctor.
If the patient has anemia, kidney or liver disease unless recommended by a doctor.
If the patient is pregnant or breastfeeding.
If the patient has a history or is suffering from stomach ulcers, bleeding or other stomach problems.
If the patient has high blood pressure or severe heart disease unless recommended by a doctor.
If the patient has anemia, kidney or liver disease unless recommended by a doctor.
If the patient is pregnant or breastfeeding.
Special Precautions
Liver Warning: Bioflu contains Paracetamol. Severe liver damage may occur if: A child takes more than 5 doses in 24 hours, which is the maximum daily amount of Paracetamol; An adult takes more than 4 g of Paracetamol in 24 hours, which is the maximum daily amount; Taken with other medicines containing Paracetamol (or Acetaminophen); An adult has 3 or more alcoholic drinks everyday while using these products. The risk of heart attack or stroke may increase if used more than directed or for longer than directed. Do not use with any other medicine containing Paracetamol, Phenylephrine or Ibuprofen (prescription or nonprescription). If the patient is not sure whether a medicine contains Paracetamol, Phenylephrine or Ibuprofen, ask a doctor. May cause drowsiness; patients should observe caution while driving or performing other tasks requiring alertness. Do not take more than the recommended dose.
Allergy Alert: Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include: Hives, (elevated, whitish or reddish patches on the skin with severe itching or pricking sensations); shock (anaphylactic), a hypersensitivity reaction resulting in generalized skin lesions and itchiness, followed by low blood pressure and often accompanied by difficulty in breathing; facial swelling; skin reddening; skin rash and skin blisters; asthma (wheezing). If an allergic reaction occurs, stop use and seek medical help right away.
Allergy Alert: Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include: Hives, (elevated, whitish or reddish patches on the skin with severe itching or pricking sensations); shock (anaphylactic), a hypersensitivity reaction resulting in generalized skin lesions and itchiness, followed by low blood pressure and often accompanied by difficulty in breathing; facial swelling; skin reddening; skin rash and skin blisters; asthma (wheezing). If an allergic reaction occurs, stop use and seek medical help right away.
Use In Pregnancy & Lactation
Contraindicated if the patient is pregnant or breastfeeding.
Adverse Reactions
Phenylephrine HCl may cause muscle shaking (tremor), restlessness, feeling of uneasiness (anxiety), insomnia/sleeplessness, nervousness, dizziness, increased blood pressure, palpitation, irregular heartbeat (arrhythmia), weakness, noisy and congested breathing (respiratory distress), and pallor.
Chlorphenamine Maleate may cause sleepiness and drowsiness. Other undesirable effects include muscle weakness, gastrointestinal discomfort, nausea, vomiting, diarrhea or constipation, dryness of the mouth, nose, and throat, difficulty urinating, ringing in the ears, visual disturbance, blurred vision, insomnia/sleeplessness, tremor, nervousness, irritability, chest tightness, increased or decreased blood pressure, and headache.
Paracetamol, when taken within the recommended dose and duration of treatment, has low incidence of side effects. Skin rashes, hypersensitivity reactions, changes in the number of white blood cells and platelets, and minor stomach and intestinal disturbances have been reported.
Chlorphenamine Maleate may cause sleepiness and drowsiness. Other undesirable effects include muscle weakness, gastrointestinal discomfort, nausea, vomiting, diarrhea or constipation, dryness of the mouth, nose, and throat, difficulty urinating, ringing in the ears, visual disturbance, blurred vision, insomnia/sleeplessness, tremor, nervousness, irritability, chest tightness, increased or decreased blood pressure, and headache.
Paracetamol, when taken within the recommended dose and duration of treatment, has low incidence of side effects. Skin rashes, hypersensitivity reactions, changes in the number of white blood cells and platelets, and minor stomach and intestinal disturbances have been reported.
Drug Interactions
Do not use these products together with sympathomimetic agents (e.g., Epinephrine, etc.) and general anesthetics (e.g., Halothane, etc.) because of the possibility for increased toxicity.
Concurrent administration with medicines for depression (e.g., Amitriptyline, Imipramine, Sertraline, Moclobemide, etc.) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic-blocking agent (e.g., Phenothiazine drugs, Phentolamine, Propranolol, etc.) before the administration of these products may decrease the effect of Phenylephrine.
The absorption of Paracetamol may be accelerated by Metoclopramide or Domperidone and absorption reduced by Cholestyramine.
Medicines which stimulate the enzymes responsible for the metabolic activation of Paracetamol such as medicines for convulsion (e.g., Phenobarbital, etc.) may increase susceptibility to the harmful effects to the liver.
Warfarin, a blood thinning medicine; an increase in the International Normalized Ratio (INR), which may serve as a sign of increased risk of bleeding, may be observed when using Paracetamol and Warfarin at the same time.
Paracetamol increases the anticoagulation effect of Warfarin.
Ibuprofen may interfere with the anti-platelet activity of aspirin, thus limiting aspirin's cardioprotective effect.
Phenylbutazone, indomethacin, salicylates (e.g., aspirin), and other NSAIDs (e.g., mefenamic acid, naproxen, diclofenac, ketoprofen), including COX-2 inhibitors (e.g., celecoxib, etoricoxib), increase the risk of stomach and intestinal bleeding in patients receiving ibuprofen.
When taken with blood thinning (anticoagulant) medicines (e.g., warfarin, dicumarol) or together with thrombolytic agents (e.g., streptokinase), ibuprofen may cause stomach and intestinal bleeding.
Tell the doctor about other medicines patient is taking, especially for cough, cold, allergy, pain or fever.
Concurrent administration with medicines for depression (e.g., Amitriptyline, Imipramine, Sertraline, Moclobemide, etc.) may result in hypertensive crisis (sudden, severe increase in blood pressure that can lead to stroke).
Taking an adrenergic-blocking agent (e.g., Phenothiazine drugs, Phentolamine, Propranolol, etc.) before the administration of these products may decrease the effect of Phenylephrine.
The absorption of Paracetamol may be accelerated by Metoclopramide or Domperidone and absorption reduced by Cholestyramine.
Medicines which stimulate the enzymes responsible for the metabolic activation of Paracetamol such as medicines for convulsion (e.g., Phenobarbital, etc.) may increase susceptibility to the harmful effects to the liver.
Warfarin, a blood thinning medicine; an increase in the International Normalized Ratio (INR), which may serve as a sign of increased risk of bleeding, may be observed when using Paracetamol and Warfarin at the same time.
Paracetamol increases the anticoagulation effect of Warfarin.
Ibuprofen may interfere with the anti-platelet activity of aspirin, thus limiting aspirin's cardioprotective effect.
Phenylbutazone, indomethacin, salicylates (e.g., aspirin), and other NSAIDs (e.g., mefenamic acid, naproxen, diclofenac, ketoprofen), including COX-2 inhibitors (e.g., celecoxib, etoricoxib), increase the risk of stomach and intestinal bleeding in patients receiving ibuprofen.
When taken with blood thinning (anticoagulant) medicines (e.g., warfarin, dicumarol) or together with thrombolytic agents (e.g., streptokinase), ibuprofen may cause stomach and intestinal bleeding.
Tell the doctor about other medicines patient is taking, especially for cough, cold, allergy, pain or fever.
Storage
Store at temperatures not exceeding 30°C.
Action
This medicine contains Phenylephrine HCl, Chlorphenamine Maleate and Paracetamol.
MedsGo Class
Cough & Cold Preparations
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