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Indications/Uses
This medicine is used for the following conditions: Control and symptomatic relief of: acute nonspecific diarrhea; chronic diarrhea associated with inflammatory bowel disease.
Reduction of number and volume of discharge in patients with ileostomies and colostomies In addition to using Loperamide for diarrhea, it is important that you replace the fluid and salt loss with the use of oral rehydration solutions (ORS) and/or by drinking plenty of fluids.
Reduction of number and volume of discharge in patients with ileostomies and colostomies In addition to using Loperamide for diarrhea, it is important that you replace the fluid and salt loss with the use of oral rehydration solutions (ORS) and/or by drinking plenty of fluids.
Dosage/Direction for Use
For Symptomatic Relief of Acute Diarrhea: Adult Dose: Take 2 capsules initially followed by 1 capsule after each loose bowel movement.
Or, as directed by a doctor.
Maximum dose is 16 mg (8 capsules) per day.
Discontinue if there is no improvement after 2 days.
For Symptomatic Relief of Chronic: Adult Dose: Take 2 capsules initially followed by 1 capsule after each loose bowel movement.
Then reduce Loperamide dose to meet individual requirements. When the optimal daily dosage has been established, administer this amount as a single dose or in divided doses. Or, as directed by a doctor.
Average Daily Maintenance Dose: Take 2 to 4 capsules/day. A dosage of five capsules (10 mg) is rarely exceeded.
If no clinical improvement is observed after treatment with 8 capsules/day (16 mg/day) for at 10 days, symptoms are unlikely to be controlled by further Loperamide administration.
If the patient misses a dose, just take the next dose if still needed for diarrhea. Do not double the dose.
Or, as directed by a doctor.
Maximum dose is 16 mg (8 capsules) per day.
Discontinue if there is no improvement after 2 days.
For Symptomatic Relief of Chronic: Adult Dose: Take 2 capsules initially followed by 1 capsule after each loose bowel movement.
Then reduce Loperamide dose to meet individual requirements. When the optimal daily dosage has been established, administer this amount as a single dose or in divided doses. Or, as directed by a doctor.
Average Daily Maintenance Dose: Take 2 to 4 capsules/day. A dosage of five capsules (10 mg) is rarely exceeded.
If no clinical improvement is observed after treatment with 8 capsules/day (16 mg/day) for at 10 days, symptoms are unlikely to be controlled by further Loperamide administration.
If the patient misses a dose, just take the next dose if still needed for diarrhea. Do not double the dose.
Overdosage
Symptoms: Loperamide overdose may result in constipation, central nervous system (CNS) depression (e.g., drowsiness and dizziness) paralytic ileus (temporary absence of intestinal movement), and urinary retention (decreased urination).
In adults, reported overdosage within 24 hours resulted in nausea after 40 mg (20 capsules) and vomiting after 60 mg (30 capsules).
Treatment: If the patient have taken more than the recommended dosage (i.e., more than 8 capsules per day), consult a doctor or a Poison Control Center right away.
In adults, reported overdosage within 24 hours resulted in nausea after 40 mg (20 capsules) and vomiting after 60 mg (30 capsules).
Treatment: If the patient have taken more than the recommended dosage (i.e., more than 8 capsules per day), consult a doctor or a Poison Control Center right away.
Administration
May be taken with or without food.
Contraindications
If allergic to Loperamide or any ingredient in the product; If it is for a child under 12 years old; If pregnant or breastfeeding; If constipated and also in whom constipation should be avoided (e.g., diarrhea resulting from infections); If abdomen is swollen or you have abdominal pain; If with acute dysentery which is characterized by blood in stools and, high fever; If with pseudomembranous colitis (diarrhea associated with antibiotics) active ulcerative colitis, meningitis, or a history of liver disease.
Special Precautions
Do not take more than the recommended dose.
Stop use and consult doctor if: Any undesirable effect occurs or acute diarrhea persists for more than two days, if symptoms worsen, if abdominal swelling or bulging develops, or if fever develops; If the patient have Acquired Immune Deficiency Syndrome (AIDS) and any signs of abdominal swelling or bulging. There have been isolated reports of toxic megacolon (rapid widening of the colon accompanied by infection or inflammation) in AIDS patients treated with Loperamide. A serious condition may develop if too much fluid has been lost by the body due to diarrhea.
Consult a doctor if any of the following conditions develop: Decreased urination; Dizziness and lightheadedness; Dryness of mouth; Increased thirst; Wrinkled skin.
Stop use and consult doctor if: Any undesirable effect occurs or acute diarrhea persists for more than two days, if symptoms worsen, if abdominal swelling or bulging develops, or if fever develops; If the patient have Acquired Immune Deficiency Syndrome (AIDS) and any signs of abdominal swelling or bulging. There have been isolated reports of toxic megacolon (rapid widening of the colon accompanied by infection or inflammation) in AIDS patients treated with Loperamide. A serious condition may develop if too much fluid has been lost by the body due to diarrhea.
Consult a doctor if any of the following conditions develop: Decreased urination; Dizziness and lightheadedness; Dryness of mouth; Increased thirst; Wrinkled skin.
Adverse Reactions
Loperamide is generally well tolerated; however, dry mouth, abdominal pain, distention or discomfort, nausea, vomiting, fatigue, flatulence, dyspepsia, constipation, epigastric pain, paralytic ileus (temporary absence of intestinal movement), and toxic megacolon (rapid widening of the colon accompanied by infection or inflammation) may occur. Loperamide may rarely cause drowsiness and dizziness.
Allergic reactions including unexplained wheezing, shortness of breath, passing out, or swelling of the face and throat have occurred very rarely.
Undesirable effects involving the skin include pruritus (itch), rash, urticaria (hives) and extremely rare cases of angioedema (rapid swelling beneath the skin) and bullous (large skin blister) eruption including Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis (severe allergic reactions characterized by separation or exfoliation of tissue) have been rarely reported.
Allergic reactions including unexplained wheezing, shortness of breath, passing out, or swelling of the face and throat have occurred very rarely.
Undesirable effects involving the skin include pruritus (itch), rash, urticaria (hives) and extremely rare cases of angioedema (rapid swelling beneath the skin) and bullous (large skin blister) eruption including Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis (severe allergic reactions characterized by separation or exfoliation of tissue) have been rarely reported.
Drug Interactions
Concomitant administration with the following may result in increased Loperamide plasma levels: Ritonavir (used to treat Human Immunodeficiency Virus);Quinidine (used to treat abnormal heart rhythms); Oral desmopressin (used to treat excessive urination); Itraconazole or ketoconazole (used to treat fungal infections); Gemfibrozil (used to lower cholesterol).
Medicines that slow down the action of the stomach and intestines (e.g., some medicines for depression and cold and allergy medications) as these may increase the constipating effect of Loperamide.
Medicines that cause drowsiness since Loperamide may also cause drowsiness
Medicines that slow down the action of the stomach and intestines (e.g., some medicines for depression and cold and allergy medications) as these may increase the constipating effect of Loperamide.
Medicines that cause drowsiness since Loperamide may also cause drowsiness
Storage
Store at temperatures not exceeding 30°C.
Action
Pharmacology: Untied Home Lormide contains Loperamide, an antidiarrheal agent which slows intestinal movement and reduces fluid and salt loss in the intestines, resulting in improved stool consistency.
MedsGo Class
Antidiarrheals
Features
Brand
United Home Lormide
Full Details
Dosage Strength
2mg
Drug Ingredients
- Loperamide
Drug Packaging
Capsule 1's
Generic Name
Loperamide Hydrochloride
Dosage Form
Capsule
Registration Number
DR-X6084
Drug Classification
Over-The-Counter (OTC)