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DIATABS Loperamide Hydrochloride 2mg Capsule 1's

NONRXDRUG-DR-XY24964-1pc
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Features

Brand
Diatabs
Full Details
Dosage Strength
2 mg
Drug Ingredients
  • Loperamide
Drug Packaging
Capsule 1's
Generic Name
Loperamide Hcl
Dosage Form
Capsule
Registration Number
DR-XY24964
Drug Classification
Over-The-Counter (OTC)
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Description

Indications/Uses

This medicine is used for the following conditions: Control and symptomatic relief of: acute non-specific diarrhea, chronic diarrhea associated with inflammatory bowel disease.
Reduction of number and volume of discharge in patients with ileostomies and colostomies.
In addition to using loperamide for diarrhea, it is important to replace that fluid and salt loss with the use of oral rehydration solution (ORS) and/or by drinking plenty of fluids.
 

Dosage/Direction for Use

For Symptomatic Relief of Acute Diarrhea: Adult Dose: Take 2 capsules initially followed by 1 capsule after each loose bowel movement.
Or, as directed by a doctor.
Maximum dose is 16 mg (8 capsules) per day.
Discontinue if there is no improvement after 2 days.
For Symptomatic Relief of Chronic Diarrhea: Adult Dose: Take 2 capsules followed by 1 capsule after each loose bowel movement.
Then reduce loperamide dose to meet individual requirements. When the optimal daily dosage has been established, administer this amount as a single dose or in divided doses.
Or, as directed by a doctor.
Average Daily Maintenance Dose: Take 2 to 4 capsules/day. A dosage of five capsules (10 mg) is rarely exceeded.
If no clinical improvement is observed after treatment with 8 capsules/day (16 mg/day) for at least 10 days, symptoms are unlikely to be controlled by further loperamide administration.
Missed Dose: If the patient missed a dose, just take the next dose if still needed for diarrhea. Do not double the dose.
 

Overdosage

Signs and Symptoms of Overdosage: Loperamide overdose may result in constipation, central nervous system (CNS) depression (e.g., drowsiness and dizziness), paralytic ileus (temporary absence of intestinal movement), and urinary retention (decreased urination).
In adults, reported overdosage within 24 hours resulted in nausea after 40 mg (20 capsules) and vomiting after 60 mg (30 capsules).
If the patient has taken more than the recommended dosage (i.e., more than 8 capsules per day), consult a doctor or a Poison Control Center right away.
 

Administration

May be taken with or without food.
 

Contraindications

If the patient is allergic to loperamide or any ingredient in the product.
If it is for a child under 12 years old.
If the patient is pregnant or breastfeeding.
If the patient is constipated and also in whom constipation should be avoided (e.g., diarrhea resulting from infections).
If the abdomen is swollen or the patient has abdominal pain.
If the patient has acute dysentery which is characterized by blood in stools and high fever.
If the patient has pseudomembranous colitis (diarrhea associated with antibiotics), active ulcerative colitis, meningitis, or a history of liver disease.
 

Special Precautions

Do not take more than the recommended dose.
Stop use and consult the doctor if: Any undesirable effect occurs or acute diarrhea persists for more than two days, if symptoms worsen, if abdominal swelling or bulging develops, or if fever develops.
The patient has Acquired Immune Deficiency Syndrome (AIDS) and any signs of abdominal swelling or bulging. There have been isolated reports of toxic megacolon (rapid widening of the colon accompanied by infection or inflammation) in AIDS patients treated with loperamide.
A serious condition may develop if too much fluid has been lost by the body due to diarrhea. Consult a doctor if any of the following conditions develop: Decreased urination, Dizziness and lightheadedness, Dryness of mouth, Increased thirst, Wrinkled skin.
 

Use In Pregnancy & Lactation

This medication is contraindicated if the patient is pregnant or breastfeeding.
 

Adverse Reactions

Loperamide is generally well tolerated; however, dry mouth, abdominal pain, distention or discomfort, nausea, vomiting, fatigue, flatulence, dyspepsia, constipation, epigastric pain, paralytic ileus (temporary absence of intestinal movement), and toxic megacolon (rapid widening of the colon accompanied by infection or inflammation) may occur. Loperamide may rarely cause drowsiness and dizziness.
Allergic reactions including unexplained wheezing, shortness of breath, passing out, or swelling of the face and throat have occurred very rarely.
Undesirable effects involving the skin include pruritus (itch), rash, urticaria (hives) and extremely rare cases of angioedema (rapid swelling beneath the skin) and bullous (large skin blister) eruption including Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis (severe allergic reactions characterized by separation or exfoliation of tissue) have been rarely reported.
 

Storage

Store at temperatures not exceeding 30°C.
 

Action

This medicine contains loperamide, an antidiarrheal agent which slows intestinal movement and reduced fluid and salt loss in the intestines, resulting in improved stool consistency.
 

MedsGo Class

Antidiarrheals
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